Design and Synthesis of a Conformationally Rigid Mimic of the Dihydropyrimidine Calcium Channel Modulator SQ 32,926
Birgit Jauk, Tetiana Pernat, C. Oliver Kappe
Molecules · 2000
doi:10.3390/50300227 (opens in a new tab)
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Abstract
A conformationally rigid polyheterocycle (3) which mimics the putative receptorbound conformation of dihydropyridine-type calcium channel modulators is prepared in a seven-step reaction sequence based on a Biginelli-type cyclocondensation reaction.
Abstract licence: CC BY
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