Novel Coumarin Derivatives with Expected Biological Activity
S. S. Abd El-Karim, M. I. El-Zahar, Z. M. Nofal
Molecules · 2000
doi:10.3390/50200099 (opens in a new tab)
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Abstract
A number of novel 3-bromo-4-methyl-7-methoxy-8-amino substituted coumarins and 2-substituted 7-bromo-6-methyl-8H-pyrano-benzimidazoles, benzoxazoles and/or benzoxazine-8-ones were synthesized for the purpose of pharmacological evaluation. Some representative compounds showed antitumor activity in vitro on Ehrlich ascites carcinoma in the preliminary testing.
Abstract licence: CC BY
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