Integrated Network Analysis and Effective Tools in Plant Systems Biology
Atsushi eFukushima, Atsushi eFukushima, Shigehiko eKanaya and 2 more
Frontiers in Plant Science · 2014
doi:10.3389/fpls.2014.00598 (opens in a new tab)
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Abstract
One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms.
Abstract licence: CC BY
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