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Meta-Network Analysis of Structural Correlation Networks Provides Insights Into Brain Network Development

Xiaohua Xu, Ping He, Pew-Thian Yap and 4 more

Frontiers in Human Neuroscience · 2019

doi:10.3389/fnhum.2019.00093 (opens in a new tab)

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Abstract

Analysis of developmental brain networks is fundamentally important for basic developmental neuroscience. In this paper, we focus on the temporally-covarying connection patterns, called meta-networks, and develop a new mathematical model for meta-network decomposition. With the proposed model, we decompose the developmental structural correlation networks of cortical thickness into five meta-networks. Each meta-network exhibits a distinctive spatial connection pattern, and its covarying trajectory highlights the temporal contribution of the meta-network along development. Systematic analysis of the meta-networks and covarying trajectories provides insights into three important aspects of brain network development.

Abstract licence: CC BY

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