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Case report: Blepharospasm in peak-dose dyskinesia may benefit from amantadine in Parkinson's disease

Qian-Ya Fan, Xiao-Dong Zhang, Ze-Di Hu and 5 more

Frontiers in Neurology · 2022

doi:10.3389/fneur.2022.961758 (opens in a new tab)

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Abstract

IntroductionBlepharospasm is uncommon in Parkinson's disease, especially in the peak-dose dyskinesia period.Case presentationWe herein present the case of a patient with PD who developed blepharospasm in the peak-dose dyskinesia period. The symptom was improved by taking amantadine.ConclusionThe current report expands the phenomenology of peak-dose dykinesia in PD to include dystonic blepharospasm. This complication of levodopa therapy may respond to amantadine despite the dystonic appearance of movements.

Abstract licence: CC BY

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