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Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review

Jin Bu, Ruilian Ding, Liangjia Zhou and 2 more

Frontiers in Immunology · 2022 · Review · CC BY

doi:10.3389/fimmu.2022.880201

Abstract

Psoriasis is a chronic autoimmune inflammatory disease that remains active for a long period, even for life in most patients. The impact of psoriasis on health is not only limited to the skin, but also influences multiple systems of the body, even mental health. With the increasing of literature on the association between psoriasis and extracutaneous systems, a better understanding of psoriasis as an autoimmune disease with systemic inflammation is created. Except for cardiometabolic diseases, gastrointestinal diseases, chronic kidney diseases, malignancy, and infections that have received much attention, the association between psoriasis and more systemic diseases, including the skin system, reproductive system, and oral and ocular systems has also been revealed, and mental health diseases draw more attention not just because of the negative mental and mood influence caused by skin lesions, but a common immune-inflammatory mechanism identified of the two systemic diseases. This review summarizes the epidemiological evidence supporting the association between psoriasis and important and/or newly reported systemic diseases in the past 5 years, and may help to comprehensively recognize the comorbidity burden related to psoriasis, further to improve the management of people with psoriasis.

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    Not in our library10.1016/j.smrv.2015.09.003

  97. 97.

    Laverde-Saad A Milan R Mohand-Saïd S LeLorier J Litvinov IV Rahme E. The Risk of Suicidal Behaviour in Individuals With Psoriasis: A Retrospective Cohort Study in Quebec, Canada. J Eur Acad Dermatol Venereol (2020 ) 34(12):e800–e2

    Not in our library10.1111/jdv.16647

  98. 98.

    Wang SH Wang J Chi CC Lin YS Liao SC Chen PE. Risk for Suicidal Behavior Among Psoriasis Patients: A Nationwide Cohort Study. Am J Clin Dermatol (2020 ) 21(3):431–9

    Not in our library10.1007/s40257-019-00489-9

  99. 99.

    Strober BE Langley RGB Menter A Magid M Porter B Fox T. No Elevated Risk for Depression, Anxiety or Suicidality With Secukinumab in a Pooled Analysis of Data From 10 Clinical Studies in Moderate-To-Severe Plaque Psoriasis. Br J Dermatol (2018 ) 178(2):e105–e7

    Not in our library10.1111/bjd.16051

  100. 100.

    Wu CY Hu HY Chou YJ Li CP Chang YT. Psoriasis Is Not a Risk Factor for Dementia: A 12-Year Nationwide Population-Based Cohort Study. Arch Dermatol Res (2020 ) 312(9):657–64

    Not in our library10.1007/s00403-020-02057-2

  101. 101.

    Lin CC Lin HC Chiu HW. Association Between Psoriasis and Dementia: A Population-Based Case-Control Study. Am J Clin Dermatol (2019 ) 20(3):457–63

    Not in our library10.1007/s40257-018-00420-8

  102. 102.

    Wong AYS Frøslev T Forbes HJ Kjaersgaard A Mulick A Mansfield K. Partner Bereavement and Risk of Psoriasis and Atopic Eczema: Cohort Studies in the U.K. And Denmark. Br J Dermatol (2020 ) 183(2):321–31

    Not in our library10.1111/bjd.18740

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    Gupta MA Gupta AK. Psoriasis Is Associated With a Higher Prevalence of Obstructive Sleep Apnea and Restless Legs Syndrome: A Possible Indication of Autonomic Activation in Psoriasis. J Clin Sleep Med (2018 ) 14(6):1085

    Not in our library10.5664/jcsm.7194

  104. 104.

    Tsai SY Chen HJ Chen C Lio CF Kuo CF Leong KH. Increased Risk of Chronic Fatigue Syndrome Following Psoriasis: A Nationwide Population-Based Cohort Study. J Transl Med (2019 ) 17(1):154

    Not in our library10.1186/s12967-019-1888-1

  105. 105.

    Skoie IM Dalen I Ternowitz T Jonsson G Kvivik I Norheim K. Fatigue in Psoriasis: A Controlled Study. Br J Dermatol (2017 ) 177(2):505–12

    Not in our library10.1111/bjd.15375

  106. 106.

    Lee JH Han K Gee HY. The Incidence Rates and Risk Factors of Parkinson Disease in Patients With Psoriasis: A Nationwide Population-Based Cohort Study. J Am Acad Dermatol (2020 ) 83(6):1688–95

    Not in our library10.1016/j.jaad.2019.07.012

  107. 107.

    Capo A Affaitati G Giamberardino MA Amerio P. Psoriasis and Migraine. J Eur Acad Dermatol Venereol (2018 ) 32(1):57–61

    Not in our library10.1111/jdv.14472

  108. 108.

    Yu S Yu CL Huang YC Tu HP Lan CE. Risk of Developing Psoriasis in Patients With Schizophrenia: A Nationwide Retrospective Cohort Study. J Eur Acad Dermatol Venereol (2017 ) 31(9):1497–504

    Not in our library10.1111/jdv.14303

  109. 109.

    Dehghani F Dehghani F Kafaie P Taghizadeh MR. Alexithymia in Different Dermatologic Patients. Asian J Psychiatr (2017 ) 25:42–5

    Not in our library10.1016/j.ajp.2016.10.011

  110. 110.

    Graetz C Woeste S Mrowietz U Ehrenthal JC. The Impact of Psychological Attachment on the Relationship Between Periodontal Health and Dental Fear in Patients With Versus Without Psoriasis: A Questionnaire-Based, Cross-Sectional Study. BMC Oral Health (2021 ) 21(1):95

    Not in our library10.1186/s12903-021-01457-8

  111. 111.

    Almeida V Taveira S Teixeira M Almeida I Rocha J Teixeira A. Emotion Regulation in Patients With Psoriasis: Correlates of Disability, Clinical Dimensions, and Psychopathology Symptoms. Int J Behav Med (2017 ) 24(4):563–70

    Not in our library10.1007/s12529-016-9617-0

  112. 112.

    Zill JM Christalle E Tillenburg N Mrowietz U Augustin M Härter M. Effects of Psychosocial Interventions on Patient-Reported Outcomes in Patients With Psoriasis: A Systematic Review and Meta-Analysis. Br J Dermatol (2019 ) 181(5):939–45

    Not in our library10.1111/bjd.17272

  113. 113.

    Islam MM Poly TN Yang HC Wu CC Li YC. Increase Risk of Multiple Sclerosis in Patients With Psoriasis Disease: An Evidence of Observational Studies. Neuroepidemiology (2019 ) 52(3-4):152–60

    Not in our library10.1159/000495112

  114. 114.

    Liu CY Tung TH Lee CY Chang KH Wang SH Chi CC. Association of Multiple Sclerosis With Psoriasis: A Systematic Review and Meta-Analysis of Observational Studies. Am J Clin Dermatol (2019 ) 20(2):201–8

    Not in our library10.1007/s40257-018-0399-9

  115. 115.

    Charlton O Phan K Smith SD Parratt J. Psoriasis in Family Members of Patients With Multiple Sclerosis. Mult Scler Relat Disord (2019 ) 36:101421

    Not in our library10.1016/j.msard.2019.101421

  116. 116.

    Yen H Chi CC. Association Between Psoriasis and Vitiligo: A Systematic Review and Meta-Analysis. Am J Clin Dermatol (2019 ) 20(1):31–40

    Not in our library10.1007/s40257-018-0394-1

  117. 117.

    Egeberg A Mallbris L Gislason GH Skov L Hansen PR. Risk of Multiple Sclerosis in Patients With Psoriasis: A Danish Nationwide Cohort Study. J Invest Dermatol (2016 ) 136(1):93–8

    Not in our library10.1038/jid.2015.350

  118. 118.

    Guido N Cices A Ibler E Huynh T Majewski S Sable K. Multiple Sclerosis Association With Psoriasis: A Large U.S. Population, Single Centre, Retrospective Cross-Sectional Study. J Eur Acad Dermatol Venereol (2017 ) 31(9):e397–e8

    Not in our library10.1111/jdv.14205

  119. 119.

    Alinaghi F Tekin HG Burisch J Wu JJ Thyssen JP Egeberg A. Global Prevalence and Bidirectional Association Between Psoriasis and Inflammatory Bowel Disease-A Systematic Review and Meta-Analysis. J Crohns Colitis (2020 ) 14(3):351–60

    Not in our library10.1093/ecco-jcc/jjz152

  120. 120.

    Fu Y Lee CH Chi CC. Association of Psoriasis With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. JAMA Dermatol (2018 ) 154(12):1417–23

    Not in our library10.1001/jamadermatol.2018.3631

  121. 121.

    Feldman SR Srivastava B Abell J Hoops T Fakharzadeh S Chakravarty S. Gastrointestinal Signs and Symptoms Related to Inflammatory Bowel Disease in Patients With Moderate-To-Severe Psoriasis. J Drugs Dermatol (2018 ) 17(12):1298–308.

    Not in our library

  122. 122.

    Egeberg A Thyssen JP Burisch J Colombel JF. Incidence and Risk of Inflammatory Bowel Disease in Patients With Psoriasis-A Nationwide 20-Year Cohort Study. J Invest Dermatol (2019 ) 139(2):316–23

    Not in our library10.1016/j.jid.2018.07.029

  123. 123.

    Masaki S Bayaraa B Imafuku S. Prevalence of Inflammatory Bowel Disease in Japanese Psoriatic Patients. J Dermatol (2019 ) 46(7):590–4

    Not in our library10.1111/1346-8138.14900

  124. 124.

    Eppinga H Poortinga S Thio HB Nijsten TEC Nuij V van der Woude CJ. Prevalence and Phenotype of Concurrent Psoriasis and Inflammatory Bowel Disease. Inflamm Bowel Dis (2017 ) 23(10):1783–9

    Not in our library10.1097/mib.0000000000001169

  125. 125.

    Egeberg A Mallbris L Gislason G Skov L. Limited Incremental Effect of Inflammatory Bowel Disease on Risk of Comorbidities in Patients With Psoriasis. J Dermatol (2017 ) 44(10):1176–7

    Not in our library10.1111/1346-8138.13658

  126. 126.

    Shaw CA Kole LCS Elewski BE. Association of Psoriasis/Psoriatic Arthritis With Inflammatory Bowel Disease Influences Management Strategy. J Eur Acad Dermatol Venereol (2019 ) 33(11):e431–e2

    Not in our library10.1111/jdv.15752

  127. 127.

    Lee JY Kang S Bae JM Jo SJ Koh SJ Park HS. Psoriasis Increases the Risk of Concurrent Inflammatory Bowel Disease: A Population-Based Nationwide Study in Korea. Indian J Dermatol Venereol Leprol (2019 ) 85(2):145–52

    Not in our library10.4103/ijdvl.ijdvl_875_17

  128. 128.

    Whitlock SM Enos CW Armstrong AW Gottlieb A Langley RG Lebwohl M. Management of Psoriasis in Patients With Inflammatory Bowel Disease: From the Medical Board of the National Psoriasis Foundation. J Am Acad Dermatol (2018 ) 78(2):383–94

    Not in our library10.1016/j.jaad.2017.06.043

  129. 129.

    Belinchón-Romero I Bellot P Romero-Pérez D Herraiz-Romero I Marco F Frances R. Non-Alcoholic Fatty Liver Disease Is Associated With Bacterial Translocation and a Higher Inflammation Response in Psoriatic Patients. Sci Rep (2021 ) 11(1):8593

    Not in our library10.1038/s41598-021-88043-8

  130. 130.

    Xu X Su L Gao Y Ding Y. The Prevalence of Nonalcoholic Fatty Liver Disease and Related Metabolic Comorbidities Was Associated With Age at Onset of Moderate to Severe Plaque Psoriasis: A Cross-Sectional Study. PloS One (2017 ) 12(1):e0169952

    Not in our library10.1371/journal.pone.0169952

  131. 131.

    Neagoe CD Farmazon AS Amzolini AM Singer CE Ianoşi SL Tutunaru CV. The Role of Non-Invasive Scores in Determining the Liver Fibrosis in Nafld and Psoriatic Patients. Rom J Morphol Embryol (2020 ) 61(2):503–11

    Not in our library10.47162/rjme.61.2.20

  132. 132.

    van der Voort EAM Wakkee M Veldt-Kok P Darwish Murad S Nijsten T. Enhanced Liver Fibrosis Test in Patients With Psoriasis, Psoriatic Arthritis and Rheumatoid Arthritis: A Cross-Sectional Comparison With Procollagen-3 N-Terminal Peptide (P3np). Br J Dermatol (2017 ) 176(6):1599–606

    Not in our library10.1111/bjd.15220

  133. 133.

    Acharya P Mathur M. Association Between Psoriasis and Celiac Disease: A Systematic Review and Meta-Analysis. J Am Acad Dermatol (2020 ) 82(6):1376–85

    Not in our library10.1016/j.jaad.2019.11.039

  134. 134.

    Egeberg A Andersen YMF Gislason GH Skov L Thyssen JP. Gallstone Risk in Adult Patients With Atopic Dermatitis and Psoriasis: Possible Effect of Overweight and Obesity. Acta Derm Venereol (2017 ) 97(5):627–31

    Not in our library10.2340/00015555-2622

  135. 135.

    Lee EB Amin M Duan L Egeberg A Wu JJ. Risk for Appendicitis, Cholecystitis, or Diverticulitis in Patients With Psoriasis. Cutis (2019 ) 103(3):175–9;e1;e2.

    Not in our library

  136. 136.

    Ogdie A Grewal SK Noe MH Shin DB Takeshita J Chiesa Fuxench ZC. Risk of Incident Liver Disease in Patients With Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis: A Population-Based Study. J Invest Dermatol (2018 ) 138(4):760–7

    Not in our library10.1016/j.jid.2017.10.024

  137. 137.

    Schonmann Y Mansfield KE Mulick A Roberts A Smeeth L Langan SM. Inflammatory Skin Diseases and the Risk of Chronic Kidney Disease: Population-Based Case-Control and Cohort Analyses. Br J Dermatol (2021 ) 185(4):772–80

    Not in our library10.1111/bjd.20067

  138. 138.

    Lee SH Kim M Han KD Lee JH. Low Hemoglobin Levels and an Increased Risk of Psoriasis in Patients With Chronic Kidney Disease. Sci Rep (2021 ) 11(1):14741

    Not in our library10.1038/s41598-021-94165-w

  139. 139.

    Lee E Han JH Bang CH Yoo SA Han KD Kim HN. Risk of End-Stage Renal Disease in Psoriatic Patients: Real-World Data From a Nationwide Population-Based Cohort Study. Sci Rep (2019 ) 9(1):16581

    Not in our library10.1038/s41598-019-53017-4

  140. 140.

    Wang CC Tang CH Huang KC Huang SY Sue YM. Increased Risk of Incident Psoriasis in End-Stage Renal Disease Patients on Chronic Hemodialysis: A Nationwide Population-Based Cohort Study. J Dermatol (2018 ) 45(9):1063–70

    Not in our library10.1111/1346-8138.14531

  141. 141.

    Grewal SK Wan J Denburg MR Shin DB Takeshita J Gelfand JM. The Risk of Iga Nephropathy and Glomerular Disease in Patients With Psoriasis: A Population-Based Cohort Study. Br J Dermatol (2017 ) 176(5):1366–9

    Not in our library10.1111/bjd.14961

  142. 142.

    Vaengebjerg S Skov L Egeberg A Loft ND. Prevalence, Incidence, and Risk of Cancer in Patients With Psoriasis and Psoriatic Arthritis: A Systematic Review and Meta-Analysis. JAMA Dermatol (2020 ) 156(4):421–9

    Not in our library10.1001/jamadermatol.2020.0024

  143. 143.

    Reddy SP Martires K Wu JJ. The Risk of Melanoma and Hematologic Cancers in Patients With Psoriasis. J Am Acad Dermatol 1区 (2017 ) 76(4):639–47.e2

    Not in our library10.1016/j.jaad.2016.09.047

  144. 144.

    Polachek A Muntyanu A Lee KA Ye JY Chandran V Cook RJ. Malignancy in Psoriatic Disease: Results From Prospective Longitudinal Cohorts. Semin Arthritis Rheum 2区 (2021 ) 51(1):144–9

    Not in our library10.1016/j.semarthrit.2020.12.008

  145. 145.

    Trafford AM Parisi R Kontopantelis E Griffiths CEM Ashcroft DM. Association of Psoriasis With the Risk of Developing or Dying of Cancer: A Systematic Review and Meta-Analysis. JAMA Dermatol (2019 ) 155(12):1390–403

    Not in our library10.1001/jamadermatol.2019.3056

  146. 146.

    Jensen P Egeberg A Gislason G Thyssen JP Skov L. Risk of Uncommon Cancers in Patients With Psoriasis: A Danish Nationwide Cohort Study. J Eur Acad Dermatol Venereol (2018 ) 32(4):601–5

    Not in our library10.1111/jdv.14610

  147. 147.

    Lee JW Jung KJ Kim TG Lee M Oh J Jee SH. Risk of Malignancy in Patients With Psoriasis: A 15-Year Nationwide Population-Based Prospective Cohort Study in Korea. J Eur Acad Dermatol Venereol (2019 ) 33(12):2296–304

    Not in our library10.1111/jdv.15783

  148. 148.

    Mason KJ Burden AD Barker J Lunt M Ali H Kleyn CE. Characteristics and Skin Cancer Risk of Psoriasis Patients With a History of Skin Cancer in Badbir. J Eur Acad Dermatol Venereol (2021 ) 35(8):e498–501

    Not in our library10.1111/jdv.17230

  149. 149.
  150. 150.

    Lima XT Cueva MA Lopes EM Alora MB. Severe Covid-19 Outcomes in Patients With Psoriasis. J Eur Acad Dermatol Venereol (2020 ) 34(12):e776–e8

    Not in our library10.1111/jdv.16867

  151. 151.

    Takeshita J Shin DB Ogdie A Gelfand JM. Risk of Serious Infection, Opportunistic Infection, and Herpes Zoster Among Patients With Psoriasis in the United Kingdom. J Invest Dermatol (2018 ) 138(8):1726–35

    Not in our library10.1016/j.jid.2018.01.039

  152. 152.

    Loft ND Halling AS Iversen L Vestergaard C Deleuran M Rasmussen MK. Concerns Related to the Coronavirus Disease 2019 Pandemic in Adult Patients With Atopic Dermatitis and Psoriasis Treated With Systemic Immunomodulatory Therapy: A Danish Questionnaire Survey. J Eur Acad Dermatol Venereol (2020 ) 34(12):e773–e6

    Not in our library10.1111/jdv.16863

  153. 153.

    Syed MN Shah M Shin DB Wan MT Winthrop KL Gelfand JM. Effect of Anti-Tumor Necrosis Factor Therapy on the Risk of Respiratory Tract Infections and Related Symptoms in Patients With Psoriasis-A Meta-Estimate of Pivotal Phase 3 Trials Relevant to Decision Making During the Covid-19 Pandemic. J Am Acad Dermatol (2021 ) 84(1):161–3

    Not in our library10.1016/j.jaad.2020.08.095

  154. 154.

    Mahil SK Dand N Mason KJ Yiu ZZN Tsakok T Meynell F. Factors Associated With Adverse Covid-19 Outcomes in Patients With Psoriasis-Insights From a Global Registry-Based Study. J Allergy Clin Immunol (2021 ) 147(1):60–71

    Not in our library10.1016/j.jaci.2020.10.007

  155. 155.

    Yiu ZZN Parisi R Lunt M Warren RB Griffiths CEM Langan SM. Risk of Hospitalization and Death Due to Infection in People With Psoriasis: A Population-Based Cohort Study Using the Clinical Practice Research Datalink. Br J Dermatol (2021 ) 184(1):78–86

    Not in our library10.1111/bjd.19052

  156. 156.

    Diotallevi F Campanati A Radi G Martina E Rizzetto G Barbadoro P. Vaccination Against Sars-Cov-2 and Psoriasis: The Three Things Every Dermatologist Should Know. J Eur Acad Dermatol Venereol (2021 ) 35(7):e428–e30

    Not in our library10.1111/jdv.17256

  157. 157.

    Orrell KA Vakharia PP Hagstrom EL Brieva J West DP Nardone B. Prevalence of Chronic Hepatitis B and C in Psoriasis Patients: A Cross-Sectional Study in a Large Us Population. J Am Acad Dermatol (2017 ) 77(3):572–3

    Not in our library10.1016/j.jaad.2017.05.020

  158. 158.

    Noe MH Grewal SK Shin DB Ogdie A Takeshita J Gelfand JM. Increased Prevalence of Hcv and Hepatic Decompensation in Adults With Psoriasis: A Population-Based Study in the United Kingdom. J Eur Acad Dermatol Venereol (2017 ) 31(10):1674–80

    Not in our library10.1111/jdv.14310

  159. 159.

    Tang KT Chen YM Chang SN Lin CH Chen DY. Psoriatic Patients With Chronic Viral Hepatitis Do Not Have an Increased Risk of Liver Cirrhosis Despite Long-Term Methotrexate Use: Real-World Data From a Nationwide Cohort Study in Taiwan. J Am Acad Dermatol (2018 ) 79(4):652–8

    Not in our library10.1016/j.jaad.2018.05.004

  160. 160.

    Chun K Afshar M Audish D Kabigting F Paik A Gallo R. Hepatitis C May Enhance Key Amplifiers of Psoriasis. J Eur Acad Dermatol Venereol (2017 ) 31(4):672–8

    Not in our library10.1111/jdv.13578

  161. 161.

    Yen YF Jen IA Chen M Lan YC Lee CY Chuang PH. Hiv Infection Increases the Risk of Incident Psoriasis: A Nationwide Population-Based Cohort Study in Taiwan. J Acquir Immune Defic Syndr (2017 ) 75(5):493–9

    Not in our library10.1097/qai.0000000000001431

  162. 162.

    Busca Arenzana C Quintana Castanedo L Chiloeches Fernández C Nieto Rodríguez D Herranz Pinto P Delgado Hierro AB. Psoriasis and Liver Damage in Hiv-Infected Patients. Cells (2021 ) 10(5):1099

    Not in our library10.3390/cells10051099

  163. 163.

    Bardazzi F Magnano M Campanati A Loconsole F Carpentieri A Potenza C. Biologic Therapies in Hiv-Infected Patients With Psoriasis: An Italian Experience. Acta Derm Venereol (2017 ) 97(8):989–90

    Not in our library10.2340/00015555-2698

  164. 164.

    Wang H Wang C Wang Z Fu X Yu G Sun L. Identification of Zfp36l1 as an Early-Onset Psoriasis Risk Gene Demonstrates Opposite Associations With Leprosy and Psoriasis in the Chinese Population. J Eur Acad Dermatol Venereol (2020 ) 34(9):e520–e3

    Not in our library10.1111/jdv.16437

  165. 165.

    Gisondi P Cazzaniga S Chimenti S Maccarone M Picardo M Girolomoni G. Latent Tuberculosis Infection in Patients With Chronic Plaque Psoriasis: Evidence From the Italian Psocare Registry. Br J Dermatol (2015 ) 172(6):1613–20

    Not in our library10.1111/bjd.13539

  166. 166.
  167. 167.

    Ng CY Huang YH Chu CF Wu TC Liu SH. Risks for Staphylococcus Aureus Colonization in Patients With Psoriasis: A Systematic Review and Meta-Analysis. Br J Dermatol (2017 ) 177(4):967–77

    Not in our library10.1111/bjd.15366

  168. 168.

    Tsai SY Chen HJ Lio CF Ho HP Kuo CF Jia X. Increased Risk of Herpes Zoster in Patients With Psoriasis: A Population-Based Retrospective Cohort Study. PloS One (2017 ) 12(8):e0179447

    Not in our library10.1371/journal.pone.0179447

  169. 169.

    Blegvad C Egeberg A Tind Nielsen TE Gislason GH Zachariae C Nybo Andersen AM. Autoimmune Disease in Children and Adolescents With Psoriasis: A Cross-Sectional Study in Denmark. Acta Derm Venereol (2017 ) 97(10):1225–9

    Not in our library10.2340/00015555-2743

  170. 170.

    Alinaghi F Calov M Kristensen LE Gladman DD Coates LC Jullien D. Prevalence of Psoriatic Arthritis in Patients With Psoriasis: A Systematic Review and Meta-Analysis of Observational and Clinical Studies. J Am Acad Dermatol (2019 ) 80(1):251–65.e19

    Not in our library10.1016/j.jaad.2018.06.027

  171. 171.
  172. 172.

    Belman S Walsh JA Carroll C Milliken M Haaland B Duffin KC. Psoriasis Characteristics for the Early Detection of Psoriatic Arthritis. J Rheumatol (2021 ) 48(10):1559–65

    Not in our library10.3899/jrheum.201123

  173. 173.
  174. 174.

    Skornicki M Prince P Suruki R Lee E Louder A. Clinical Burden of Concomitant Joint Disease in Psoriasis: A Us-Linked Claims and Electronic Health Records Database Analysis. Adv Ther (2021 ) 38(5):2458–71

    Not in our library10.1007/s12325-021-01698-7

  175. 175.

    Mease PJ Palmer JB Hur P Strober BE Lebwohl M Karki C. Utilization of the Validated Psoriasis Epidemiology Screening Tool to Identify Signs and Symptoms of Psoriatic Arthritis Among Those With Psoriasis: A Cross-Sectional Analysis From the Us-Based Corrona Psoriasis Registry. J Eur Acad Dermatol Venereol (2019 ) 33(5):886–92

    Not in our library10.1111/jdv.15443

  176. 176.

    Salaffi F Di Carlo M Luchetti MM Di Donato E Campanati A Benfaremo D. A Validation Study of the Simple Psoriatic Arthritis Screening (Sipas) Questionnaire to Screen Psoriasis Patients for Psoriatic Arthritis. Clin Exp Rheumatol (2018 ) 36(1):127–35.

    Not in our library

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  178. 178.

    Zuliani F Zabotti A Errichetti E Tinazzi I Zanetti A Carrara G. Ultrasonographic Detection of Subclinical Enthesitis and Synovitis: A Possible Stratification of Psoriatic Patients Without Clinical Musculoskeletal Involvement. Clin Exp Rheumatol (2019 ) 37(4):593–9.

    Not in our library

  179. 179.

    Schmidt A Glimm AM Haugen IK Hoff P Schmittat G Burmester GR. Detection of Subclinical Skin Manifestation in Patients With Psoriasis and Psoriatic Arthritis by Fluorescence Optical Imaging. Arthritis Res Ther (2020 ) 22(1):192

    Not in our library10.1186/s13075-020-02277-x

  180. 180.

    Kathuria P Gordon KB Silverberg JI. Association of Psoriasis and Psoriatic Arthritis With Osteoporosis and Pathological Fractures. J Am Acad Dermatol (2017 ) 76(6):1045–53.e3

    Not in our library10.1016/j.jaad.2016.11.046

  181. 181.

    Modalsli EH Åsvold BO Romundstad PR Langhammer A Hoff M Forsmo S. Psoriasis, Fracture Risk and Bone Mineral Density: The Hunt Study, Norway. Br J Dermatol (2017 ) 176(5):1162–9

    Not in our library10.1111/bjd.15123

  182. 182.

    Lee JW Min C Bang CH Kwon BC Choi HG. Psoriasis Is Associated With an Increased Risk of Osteoporosis: Follow-Up and Nested Case-Control Studies Using a National Sample Cohort. Osteoporos Int (2021 ) 32(3):529–38

    Not in our library10.1007/s00198-020-05724-2

  183. 183.

    Sepehri NZ Raeisi T Razi B Janmohammadi P Darand M Alizadeh S. The Association Between Psoriasis and Psoriatic Arthritis With the Risk of Osteoporosis, Osteopenia and Bone Fractures: A Systematic Review and Meta-Analysis. Int J Clin Pract (2021 ) 75(11):e14630

    Not in our library10.1111/ijcp.14630

  184. 184.

    Zander N Schäfer I Radtke M Jacobi A Heigel H Augustin M. Dermatological Comorbidity in Psoriasis: Results From a Large-Scale Cohort of Employees. Arch Dermatol Res (2017 ) 309(5):349–56

    Not in our library10.1007/s00403-017-1741-4

  185. 185.

    Caldarola G De Simone C Talamonti M Moretta G Fossati B Bianchi L. Prevalence of Cutaneous Comorbidities in Psoriatic Patients and Their Impact on Quality of Life. Eur J Dermatol (2019 ) 29(2):192–6

    Not in our library10.1684/ejd.2019.3529

  186. 186.

    Phan K Ramachandran V Smith SD. Association Between Pemphigus and Psoriasis: A Systematic Review and Meta-Analysis. Dermatol Online J (2020 ) 26(8):13030/qt5g78q4f4

    Not in our library10.5070/d3268049899

  187. 187.

    Chiu YW Chen YD Hua TC Wu CH Liu HN Chang YT. Comorbid Autoimmune Diseases in Patients With Pemphigus: A Nationwide Case-Control Study in Taiwan. Eur J Dermatol (2017 ) 27(4):375–81

    Not in our library10.1684/ejd.2017.3060

  188. 188.

    Ho YH Hu HY Chang YT Li CP Wu CY. Psoriasis Is Associated With Increased Risk of Bullous Pemphigoid: A Nationwide Population-Based Cohort Study in Taiwan. J Dermatol (2019 ) 46(7):604–9

    Not in our library10.1111/1346-8138.14902

  189. 189.

    Kridin K Bergman R. Association Between Bullous Pemphigoid and Psoriasis: A Case-Control Study. J Am Acad Dermatol (2017 ) 77(2):370–2

    Not in our library10.1016/j.jaad.2017.02.057

  190. 190.

    Damiani G Cazzaniga S Conic RR Naldi L. Pruritus Characteristics in a Large Italian Cohort of Psoriatic Patients. J Eur Acad Dermatol Venereol (2019 ) 33(7):1316–24

    Not in our library10.1111/jdv.15539

  191. 191.

    Reszke R Białynicki-Birula R Szepietowski JC. Itch in Psoriasis: A New Look at Well-Known Subject. Acta Derm Venereol (2019 ) 99(4):429–34

    Not in our library10.2340/00015555-3147

  192. 192.

    Andersen YMF Augustin M Petersen J Hagenström K Mallbris L Burge R. Characteristics and Prevalence of Plaque Psoriasis in Patients With Palmoplantar Pustulosis. Br J Dermatol (2019 ) 181(5):976–82

    Not in our library10.1111/bjd.17832

  193. 193.

    Claßen A Buhl T Schubert S Worm M Bauer A Geier J. The Frequency of Specific Contact Allergies Is Reduced in Patients With Psoriasis. Br J Dermatol (2019 ) 180(2):315–20

    Not in our library10.1111/bjd.17080

  194. 194.

    Kirsten N Mohr N Maul JT Augustin M. Incidence of Atopic Conditions in People With Psoriasis: A Population-Based Analysis. Eur J Dermatol (2021 ) 31(1):60–4

    Not in our library10.1684/ejd.2021.3963

  195. 195.

    Wu T Duan X Chen S Chen X Yu R Yu X. Association Between Psoriasis and Erectile Dysfunction: A Meta-Analysis. J Sex Med (2018 ) 15(6):839–47

    Not in our library10.1016/j.jsxm.2018.04.630

  196. 196.

    Zhao S Wang J Xie Q Liu Y Luo L Zhu Z. High Prevalence of Erectile Dysfunction in Men With Psoriasis: Evidence From a Systematic Review and Meta-Analysis. Int J Impot Res (2019 ) 31(2):74–84

    Not in our library10.1038/s41443-018-0093-8

  197. 197.

    Egeberg A Hansen PR Gislason GH Skov L Thyssen JP. Erectile Dysfunction in Male Adults With Atopic Dermatitis and Psoriasis. J Sex Med (2017 ) 14(3):380–6

    Not in our library10.1016/j.jsxm.2016.12.233

  198. 198.

    Hillary T Gutermuth J. Should Psoriasis Be Considered a Risk Factor for Hypogonadism in Male Patients? A Monocentric, Prospective, Observational Pilot Study. J Eur Acad Dermatol Venereol (2017 ) 31(4):e197–e8

    Not in our library10.1111/jdv.13944

  199. 199.

    Molina-Leyva A Salvador-Rodriguez L Martinez-Lopez A Ruiz-Carrascosa JC Arias-Santiago S. Association Between Psoriasis and Sexual and Erectile Dysfunction in Epidemiologic Studies: A Systematic Review. JAMA Dermatol (2019 ) 155(1):98–106

    Not in our library10.1001/jamadermatol.2018.3442

  200. 200.

    Xie W Huang H Ji L Zhang Z. Maternal and Neonatal Outcomes in Pregnant Women With Psoriasis and Psoriatic Arthritis: A Systematic Review and Meta-Analysis. Rheumatology (Oxford) (2021 ) 60(9):4018–28

    Not in our library10.1093/rheumatology/keab357

  201. 201.

    Wang J Ke R Shi W Yan X Wang Q Zhang Q. Association Between Psoriasis and Asthma Risk: A Meta-Analysis. Allergy Asthma Proc (2018 ) 39(2):103–9

    Not in our library10.2500/aap.2018.39.4109

  202. 202.

    Kim SY Min C Oh DJ Choi HG. Increased Risk of Psoriasis in Children and Elderly Patients With Asthma: A Longitudinal Follow-Up Study Using a National Sample Cohort. Int Forum Allergy Rhinol (2019 ) 9(11):1304–10

    Not in our library10.1002/alr.22429

  203. 203.

    Liu J Martin A Thatiparthi A Wu JJ. Effect Modification by Smoking Status on the Association Between Psoriasis and Chronic Obstructive Pulmonary Disease Among Adults in the USA. Acta Derm Venereol (2021 ) 101(8):adv00518

    Not in our library10.2340/00015555-3864

  204. 204.

    González-Álvarez L García-Martín JM García-Pola MJ. Association Between Geographic Tongue and Psoriasis: A Systematic Review and Meta-Analyses. J Oral Pathol Med (2019 ) 48(5):365–72

    Not in our library10.1111/jop.12840

  205. 205.

    Michalek IM Loring B John SM. A Systematic Review of Worldwide Epidemiology of Psoriasis. J Eur Acad Dermatol Venereol (2017 ) 31(2):205–12

    Not in our library10.1111/jdv.13854

  206. 206.

    Al Qahtani NA Deepthi A Alhussain NM Al Shahrani BAM Alshehri H Alhefzi A. Association of Geographic Tongue and Fissured Tongue With Abo Blood Group Among Adult Psoriasis Patients: A Novel Study From a Tertiary Care Hospital in Saudi Arabia. Oral Surg Oral Med Oral Pathol Oral Radiol (2019 ) 127(6):490–7

    Not in our library10.1016/j.oooo.2019.01.080

  207. 207.

    Monshi B Grabovac S Gulz L Ellersdorfer C Vujic M Richter L. Psoriasis Is Associated With Fissured Tongue But Not Geographic Tongue: A Prospective, Cross-Sectional, Case-Control Study. J Dtsch Dermatol Ges (2021 ) 19(8):1170–6

    Not in our library10.1111/ddg.14451

  208. 208.

    Olejnik M Osmola-Mańkowska A Ślebioda Z Adamski Z Dorocka-Bobkowska B. Oral Mucosal Lesions in Psoriatic Patients Based on Disease Severity and Treatment Approach. J Oral Pathol Med (2020 ) 49(8):822–8

    Not in our library10.1111/jop.13095

  209. 209.

    Ungprasert P Wijarnpreecha K Wetter DA. Periodontitis and Risk of Psoriasis: A Systematic Review and Meta-Analysis. J Eur Acad Dermatol Venereol (2017 ) 31(5):857–62

    Not in our library10.1111/jdv.14051

  210. 210.

    Egeberg A Mallbris L Gislason G Hansen PR Mrowietz U. Risk of Periodontitis in Patients With Psoriasis and Psoriatic Arthritis. J Eur Acad Dermatol Venereol (2017 ) 31(2):288–93

    Not in our library10.1111/jdv.13814

  211. 211.

    Mendes VS Cota LOM Costa AA Oliveira A Costa FO. Periodontitis as Another Comorbidity Associated With Psoriasis: A Case-Control Study. J Periodontol (2019 ) 90(4):358–66

    Not in our library10.1002/jper.18-0394

  212. 212.

    Painsi C Hirtenfelder A Lange-Asschenfeldt B Quehenberger F Wolf P. The Prevalence of Periodontitis Is Increased in Psoriasis and Linked to Its Inverse Subtype. Skin Pharmacol Physiol (2017 ) 30(6):324–8

    Not in our library10.1159/000481544

  213. 213.

    Lee CY Chen HC Lin HW Huang JY Lin TL Yang CH. Increased Risk of Keratopathy After Psoriasis: A Nationwide Population-Based Study. PloS One (2018 ) 13(7):e0201285

    Not in our library10.1371/journal.pone.0201285

  214. 214.

    Dai YX Tai YH Lee DD Chang YT Chen TJ Chen MH. Risk of Retinal Diseases in Patients With Psoriasis: A Population-Based Cohort Study in Taiwan. J Dermatol (2021 ) 48(10):1550–6

    Not in our library10.1111/1346-8138.16062

  215. 215.

    Chi CC Tung TH Wang J Lin YS Chen YF Hsu TK. Risk of Uveitis Among People With Psoriasis: A Nationwide Cohort Study. JAMA Ophthalmol (2017 ) 135(5):415–22

    Not in our library10.1001/jamaophthalmol.2017.0569

  216. 216.

    Abbagani S Kamath YS Nayak S. A Study on Ocular Morbidity Among Patients With Psoriasis Visiting a Tertiary Care Hospital in Karnataka, Southern India. Ocul Immunol Inflamm (2019 ) 27(4):531–4

    Not in our library10.1080/09273948.2017.1414271

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    Hahn HJ Kwak SG Kim DK Kim JY. Association of Behçet Disease With Psoriasis and Psoriatic Arthritis. Sci Rep (2021 ) 11(1):2531

    Not in our library10.1038/s41598-021-81972-4

  219. 219.

    Liu JM Lin CY Chang FW Liu YP Liang CP Hsu RJ. Increased Risk of Psoriasis Following Scabies Infection: A Nationwide Population-Based Matched-Cohort Study. J Dermatol (2018 ) 45(3):302–8

    Not in our library10.1111/1346-8138.14221

  220. 220.

    Schaffer JV. Pediatric Game Changers∗: Serious Infection Risk in Children With Psoriasis on Systemic Treatment: A Propensity Score-Matched Population-Based Study. J Am Acad Dermatol (2021 ) 84(6):1797

    Not in our library10.1016/j.jaad.2021.02.007

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