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Potential SARS-CoV-2 Preimmune IgM Epitopes

Velizar Shivarov, Velizar Shivarov, Peter K. Petrov and 1 more

Frontiers in Immunology · 2020

doi:10.3389/fimmu.2020.00932 (opens in a new tab)

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Abstract

While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found: two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine development, here we describe briefly these potential epitopes in comparison to mimotopes representing peptides of SARS-CoV, HCoV 229E and OC43.

Abstract licence: CC BY

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