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Corrigendum: Low-Dose Radiation Can Cause Epigenetic Alterations Associated With Impairments in Both Male and Female Reproductive Cell

Chi Tim Leung, Chi Tim Leung, Yi Yang and 22 more

Frontiers in Genetics · 2022

doi:10.3389/fgene.2022.945115 (opens in a new tab)

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Abstract

Two human ovarian cancer cells (SKOV3 and COV434) and two mouse testicular germ cells (GC-1 and TM4) were cultured under the conditions described in Supplementary Table 1. Only human and mouse cell lines (not primary cells) were used, and these were purchased from an international company. In accordance with the national legislation and the institutional requirements, the Human Research Ethics Committee of The University of Hong Kong waived the requirement for ethical approval and written informed consent for participants in this study. The cells were cultured at 37 °C under 95 % air and 5 % carbon dioxide. For the ionizing radiation exposure, the cells were seeded onto 6 well plate 1 day before exposure to 10 cGy of X-ray (320 kV, 2 mA) for 1 min (X-RAD 320 x-ray system).

Abstract licence: CC BY

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