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A Computation using mutually exclusive processing is sufficient to identify specific Hedgehog signalling components

Spencer J Spratt

Frontiers in Genetics · 2013

doi:10.3389/fgene.2013.00284 (opens in a new tab)

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Abstract

A system of more than one part can be deciphered by observing differences between the parts. A simple way to do this is by recording something absolute displaying a trait in one part and not in another: in other words, mutually exclusive computation. Conditional directed expression in vivo offers processing in more than one part of the system giving increased computation power for biological systems analysis. Here, I report the consideration of these aspects in the development of an in vivo screening assay that appears sufficient to identify components specific to a system.

Abstract licence: CC BY

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