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Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema

Danapriyaa Dharmalingam, Janani Semalaiyappan, Sankari Thirumal and 1 more

Frontiers in Cellular and Infection Microbiology · 2025

doi:10.3389/fcimb.2025.1624288 (opens in a new tab)

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Abstract

Facklamia is an emerging pathogen in human beings and only a few clinical cases were reported in the literature. We detected the presence of this unusual microbe among the skin flora of three patients with filarial lymphedema in a 16S rRNA-based metagenomic study on the skin microbiome. To our knowledge, this is the first report of detection of this microbe in patients affected with filarial lymphedema. Further investigations are required to elucidate the role of Facklamia in secondary skin and soft tissue infection of filarial lymphedema patients.

Abstract licence: CC BY

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