Successful Treatment of Balamuthia mandrillaris Granulomatous Amebic Encephalitis with Nitroxoline
Natasha Spottiswoode, Douglas Pet, Annie Kim and 15 more
Emerging Infectious Diseases · 2023
doi:10.3201/eid2901.221531 (opens in a new tab)
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Abstract
A patient in California, USA, with rare and usually fatal Balamuthia mandrillaris granulomatous amebic encephalitis survived after receiving treatment with a regimen that included the repurposed drug nitroxoline. Nitroxoline, which is a quinolone typically used to treat urinary tract infections, was identified in a screen for drugs with amebicidal activity against Balamuthia.
Abstract licence: CC BY
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