Rifampicin Resistance in Tuberculosis Outbreak, London, England
Claire Jenkins, Alleyna P. Claxton, Robert J. Shorten and 2 more
Emerging Infectious Diseases · 2005
doi:10.3201/eid1106.041262 (opens in a new tab)
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Abstract
Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance–determining region.
Abstract licence: CC BY
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