Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern
Kerry H. Lok, William H. Benjamin, Michael E. Kimerling and 5 more
Emerging Infectious Diseases · 2002
doi:10.3201/eid0811.020292 (opens in a new tab)
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Abstract
We conducted a population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2,452 isolates, 1,013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided.
Abstract licence: CC BY
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