First Shiga Toxin-Producing Escherichia coli Isolate from a Patient with Hemolytic Uremic Syndrome, Brazil

Syndrome, BrazilTo the Editor: Infection by Shiga toxin (Stx)-producing Escherichia coli (STEC), particularly strains of serotype O157:H7, can cause sporadic cases and outbreaks of diarrhea, hemorrhagic colitis (HC), and hemolytic uremic syndrome (HUS) (1).Some other serotypes (e.g., O26:H11, O111:H8, O111:NM, and O113:H21) share a similar pathogenic potential.STEC are distributed worldwide, but most of the HC and HUS cases were reported from industrialized nations of the Northern and Southern Hemispheres (2).In South America, HUS is a major cause of acute renal failure in infants in Argentina (3) and Chile (4).However, in Brazil human STEC infections have been restricted to sporadic cases of nonbloody diarrhea (5,6).Although a high frequency of STEC strains was recently found in foods and animal reservoirs (7,8), only some of the serotypes identified in animals (8) were recognized as causes of human illness (e.g., O157:H7, O22:H16, O82:H8, and NT:H21).Moreover, there is currently no nationwide surveillance system for HUS in Brazil, and STEC-associated HUS has not been previously reported in our country.We describe the case of an 8month-old boy from a northeastern state in Brazil, who was admitted to the emergency room of Hospital São Paulo, São Paulo, on March 17, 2001; the boy had anemia, oliguria, and edema of lower extremities.He had an acute diarrheal prodromal illness 3 weeks before hospital admission.On the same day as admission, respiratory failure developed, and the child was transferred to the pediatric intensive-

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