Skip to content
naulon

No retraction, correction or concern found when last checked on Nov 1, 2026.

First Isolation of La Crosse Virus from Naturally Infected Aedes albopictus

Reid R. Gerhardt, Kristy L. Gottfried, Charles S. Apperson and 6 more

Emerging Infectious Diseases · 2001

doi:10.3201/eid0705.017506

Abstract

La Crosse (LAC) virus, a California serogroup bunyavirus, is the leading cause of pediatric arboviral encephalitis in the United States and an emerging disease in Tennessee, West Virginia, and North Carolina. Human cases of LAC encephalitis in Tennessee and North Carolina have increased above endemic levels during 1997 to 1999 and may represent an expansion of a new southeastern endemic focus. This report describes the isolation of LAC virus from the exotic mosquito Aedes albopictus. The discovery of LAC virus in wild populations of Ae. albopictus coupled with its expanding distribution in the southeastern United States, suggests that this mosquito may become an important accessory vector, potentially increasing the number of human cases in endemic foci or expanding the range of the disease.

References 17

  1. 1.

    Grimstad P. R., Kobayashi J. F., Zhang M. B., Craig G. B. Recently introduced Aedes albopictus in the United States: potential vector of La Crosse virus (Bunyaviridae: California serogroup). J Am Mosq Control Assoc. 1989;5(3):422-427.

    Not in our library

  2. 2.

    Jones T. F., Craig A. S., Nasci R. S., Patterson L. E., Erwin P. C., Gerhardt R. R., Ussery X. T., Schaffner W. Newly recognized focus of La Crosse encephalitis in Tennessee. Clin Infect Dis. 1999;28(1):93-97.

    Not in our library10.1086/515087

  3. 3.

    Jones T. F., Erwin P. C., Craig A. S., Baker P., Touhey K. E., Patterson L. E., Schaffner W. Serological survey and active surveillance for La Crosse virus infections among children in Tennessee. Clin Infect Dis. 2000;31(5):1284-1287.

    Not in our library10.1086/317458

  4. 4.

    Kappus K. D., Calisher C. H., Baron R. C., Davenport J., Francy D. B., Williams R. M. La Crosse virus infection and disease in western North Carolina. Am J Trop Med Hyg. 1982;31(3 Pt 1):556-560.

    Not in our library10.4269/ajtmh.1982.31.556

  5. 5.

    Kelsey D. S., Smith B. California virus encephalitis in North Carolina. N C Med J. 1978;39(11):654-656.

    Not in our library

  6. 6.

    Kjer K. M., Baldridge G. D., Fallon A. M. Mosquito large subunit ribosomal RNA: simultaneous alignment of primary and secondary structure. Biochim Biophys Acta. 1994;1217(2):147-155.

    Not in our library10.1016/0167-4781(94)90028-0

  7. 7.

    Kuno G., Mitchell C. J., Chang G. J., Smith G. C. Detecting bunyaviruses of the Bunyamwera and California serogroups by a PCR technique. J Clin Microbiol. 1996;34(5):1184-1188.

    Not in our library10.1128/jcm.34.5.1184-1188.1996

  8. 8.
  9. 9.

    Nasci R. S., Mitchell C. J. Arbovirus titer variation in field-collected mosquitoes. J Am Mosq Control Assoc. 1996;12(2 Pt 1):167-171.

    Not in our library

  10. 10.

    Nasci R. S., Moore C. G., Biggerstaff B. J., Panella N. A., Liu H. Q., Karabatsos N., Davis B. S., Brannon E. S. La Crosse encephalitis virus habitat associations in Nicholas County, West Virginia. J Med Entomol. 2000;37(4):559-570.

    Not in our library10.1603/0022-2585-37.4.559

  11. 11.

    Reno H. E., Vodkin M. H., Novak R. J. Differentiation of Aedes triseriatus (Say) from Aedes hendersoni Cockerell (Diptera: Culicidae) by restriction fragment length polymorphisms of amplified ribosomal DNA. Am J Trop Med Hyg. 2000;62(2):193-199.

    Not in our library10.4269/ajtmh.2000.62.193

  12. 12.

    Steinly B. A., Novak R. J., Webb D. W. A new method for monitoring mosquito oviposition in artificial and natural containers. J Am Mosq Control Assoc. 1991;7(4):649-650.

    Not in our library

  13. 13.

    Szumlas D. E., Apperson C. S., Hartig P. C., Francy D. B., Karabatsos N. Seroepidemiology of La Crosse virus infection in humans in western North Carolina. Am J Trop Med Hyg. 1996;54(4):332-337.

    Not in our library10.4269/ajtmh.1996.54.332

  14. 14.

    Szumlas D. E., Apperson C. S., Powell E. E., Hartig P., Francy D. B., Karabotsos N. Relative abundance and species composition of mosquito populations (Diptera:Culicidae) in a La Crosse virus-endemic area in western North Carolina. J Med Entomol. 1996;33(4):598-607.

    Not in our library10.1093/jmedent/33.4.598

  15. 15.

    Szumlas D. E., Apperson C. S., Powell E. E. Seasonal occurrence and abundance of Aedes triseriatus and other mosquitoes in a La Crosse virus-endemic area in western North Carolina. J Am Mosq Control Assoc. 1996;12(2 Pt 1):184-193.

    Not in our library

  16. 16.

    Tesh R. B. Experimental studies on the transovarial transmission of Kunjin and San Angelo viruses in mosquitoes. Am J Trop Med Hyg. 1980;29(4):657-666.

    Not in our library10.4269/ajtmh.1980.29.657

  17. 17.

    Tesh R. B., Gubler D. J. Laboratory studies of transovarial transmission of La Crosse and other arboviruses by Aedes albopictus and Culex fatigans. Am J Trop Med Hyg. 1975;24(5):876-880.

    Not in our library10.4269/ajtmh.1975.24.876

Cited by papers we hold 3

Reads

Read by people on this page

None yet.

Checked or read by AI through naulon

None yet.

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.

Are you an author?

Is this your paper?

Claim it to add your note and be paid when agents cite it. Free.