Bacteroides fragilis Enterotoxin Gene Sequences in Patients with Inflammatory Bowel Disease

Abstract

We identified enterotoxigenic Bacteroides fragilis in stool specimens of patients with inflammatory bowel disease and other gastrointestinal disorders. The organism was detected in 11 (13.2%) of 83 patients with inflammatory bowel disease. Of 57 patients with active disease, 19.3% were toxin positive; none of those with inactive disease had specimens positive for enterotoxigenic Bacteroides fragilis gene sequences.

References 18

1. 1.

   Doré J., Sghir A., Hannequart-Gramet G., Corthier G., Pochart P. Design and evaluation of a 16S rRNA-targeted oligonucleotide probe for specific detection and quantitation of human faecal Bacteroides populations. Syst Appl Microbiol. 1998;21(1):65-71.

   Not in our library10.1016/s0723-2020(98)80009-x

2. 2.

   Gorbach S. L., Bartlett J. G. Anaerobic infections. 1. N Engl J Med. 1974;290(21):1177-1184.

   Not in our library10.1056/nejm197405232902106

3. 3.

   Hermens D. J., Miner P. B. Exacerbation of ulcerative colitis. Gastroenterology. 1991;101(1):254-262.

   Not in our library10.1016/0016-5085(91)90487-6

4. 4.

   Kato N., Ou C. Y., Kato H., Bartley S. L., Luo C. C., Killgore G. E., Ueno K. Detection of toxigenic Clostridium difficile in stool specimens by the polymerase chain reaction. J Infect Dis. 1993;167(2):455-458.

   Not in our library10.1093/infdis/167.2.455

5. 5.

   Moore W. E., Cato E. P., Holdeman L. V. Some current concepts in intestinal bacteriology. Am J Clin Nutr. 1978;31(10 Suppl):S33-S42.

   Not in our library10.1093/ajcn/31.10.s33

6. 6.

   Myers L. L., Firehammer B. D., Shoop D. S., Border M. M. Bacteroides fragilis: a possible cause of acute diarrheal disease in newborn lambs. Infect Immun. 1984;44(2):241-244.

   Not in our library10.1128/iai.44.2.241-244.1984

7. 7.

   Onderdonk A. B., Cisneros R. L., Bronson R. T. Enhancement of experimental ulcerative colitis by immunization with Bacteroides vulgatus. Infect Immun. 1983;42(2):783-788.

   Not in our library10.1128/iai.42.2.783-788.1983

8. 8.

   Pantosti A., Cerquetti M., Colangeli R., D'Ambrosio F. Detection of intestinal and extra-intestinal strains of enterotoxigenic Bacteroides fragilis by the HT-29 cytotoxicity assay. J Med Microbiol. 1994;41(3):191-196.

   Not in our library10.1099/00222615-41-3-191

9. 9.

   Pantosti A., Menozzi M. G., Frate A., Sanfilippo L., D'Ambrosio F., Malpeli M. Detection of enterotoxigenic Bacteroides fragilis and its toxin in stool samples from adults and children in Italy. Clin Infect Dis. 1997;24(1):12-16.

   Not in our library10.1093/clinids/24.1.12

10. 10.

    Sack R. B., Albert M. J., Alam K., Neogi P. K., Akbar M. S. Isolation of enterotoxigenic Bacteroides fragilis from Bangladeshi children with diarrhea: a controlled study. J Clin Microbiol. 1994;32(4):960-963.

    Not in our library10.1128/jcm.32.4.960-963.1994

11. 11.

    Sack R. B., Myers L. L., Almeido-Hill J., Shoop D. S., Bradbury W. C., Reid R., Santosham M. Enterotoxigenic Bacteroides fragilis: epidemiologic studies of its role as a human diarrhoeal pathogen. J Diarrhoeal Dis Res. 1992;10(1):4-9.

    Not in our library

12. 12.

    San Joaquin V. H., Griffis J. C., Lee C., Sears C. L. Association of Bacteroides fragilis with childhood diarrhea. Scand J Infect Dis. 1995;27(3):211-215.

    Not in our library10.3109/00365549509019011

13. 13.

    Sartor R. B. Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease. Gastroenterol Clin North Am. 1995;24(3):475-507.

    Not in our library

14. 14.

    Shetab R., Cohen S. H., Prindiville T., Tang Y. J., Cantrell M., Rahmani D., Silva J. Detection of Bacteroides fragilis enterotoxin gene by PCR. J Clin Microbiol. 1998;36(6):1729-1732.

    Not in our library10.1128/jcm.36.6.1729-1732.1998

15. 15.

    Simon G. L., Gorbach S. L. Intestinal flora in health and disease. Gastroenterology. 1984;86(1):174-193.

    Not in our library

16. 16.

    Van Tassell R. L., Lyerly D. M., Wilkins T. D. Purification and characterization of an enterotoxin from Bacteroides fragilis. Infect Immun. 1992;60(4):1343-1350.

    Not in our library10.1128/iai.60.4.1343-1350.1992

17. 17.

    Van de Merwe J. P., Schröder A. M., Wensinck F., Hazenberg M. P. The obligate anaerobic faecal flora of patients with Crohn's disease and their first-degree relatives. Scand J Gastroenterol. 1988;23(9):1125-1131.

    Not in our library10.3109/00365528809090179

18. 18.

    Weikel C. S., Grieco F. D., Reuben J., Myers L. L., Sack R. B. Human colonic epithelial cells, HT29/C1, treated with crude Bacteroides fragilis enterotoxin dramatically alter their morphology. Infect Immun. 1992;60(2):321-327.

    Not in our library10.1128/iai.60.2.321-327.1992

Cited by papers we hold 10

• Colorectal cancer: the facts in the case of the microbiota · 2022
  No notice
• The microbiome in inflammatory bowel diseases: from pathogenesis to therapy · 2020
  No notice
• Enterotoxigenic Bacteroides fragilis induces the stemness in colorectal cancer via upregulating histone demethylase JMJD2B · 2020
  No notice
• Enterotoxigenic Bacteroides fragilis: A Possible Etiological Candidate for Bacterially-Induced Colorectal Precancerous and Cancerous Lesions · 2020
  No notice
• Pathobiont release from dysbiotic gut microbiota biofilms in intestinal inflammatory diseases: a role for iron? · 2019
  No notice
• Human Gut Microbiota and Gastrointestinal Cancer · 2018
  No notice
• Influence of diet on the gut microbiome and implications for human health · 2017
  No notice
• Microbiome, Metabolome and Inflammatory Bowel Disease · 2016
  No notice
• Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis · 2014
  No notice
• Characterization of adherent bacteroidales from intestinal biopsies of children and young adults with inflammatory bowel disease. · 2013
  Not checked

Reads

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.