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Food-Related Illness and Death in the United States

Paul S. Mead, Laurence Slutsker, Vance Dietz and 5 more

Emerging Infectious Diseases · 1999 · Review

doi:10.3201/eid0505.990502

Abstract

To better quantify the impact of foodborne diseases on health in the United States, we compiled and analyzed information from multiple surveillance systems and other sources. We estimate that foodborne diseases cause approximately 76 million illnesses, 325,000 hospitalizations, and 5,000 deaths in the United States each year. Known pathogens account for an estimated 14 million illnesses, 60, 000 hospitalizations, and 1,800 deaths. Three pathogens, Salmonella, Listeria, and Toxoplasma, are responsible for 1,500 deaths each year, more than 75% of those caused by known pathogens, while unknown agents account for the remaining 62 million illnesses, 265,000 hospitalizations, and 3,200 deaths. Overall, foodborne diseases appear to cause more illnesses but fewer deaths than previously estimated.

References 48

  1. 1.

    Addiss D. G., Davis J. P., Roberts J. M., Mast E. E. Epidemiology of giardiasis in Wisconsin: increasing incidence of reported cases and unexplained seasonal trends. Am J Trop Med Hyg. 1992;47(1):13-19.

    Not in our library10.4269/ajtmh.1992.47.13

  2. 2.

    Bean N. H., Martin S. M., Bradford H. PHLIS: an electronic system for reporting public health data from remote sites. Am J Public Health. 1992;82(9):1273-1276.

    Not in our library10.2105/ajph.82.9.1273

  3. 3.

    Bell B. P., Shapiro C. N., Alter M. J., Moyer L. A., Judson F. N., Mottram K., Fleenor M., Ryder P. L., Margolis H. S. The diverse patterns of hepatitis A epidemiology in the United States-implications for vaccination strategies. J Infect Dis. 1998;178(6):1579-1584.

    Not in our library10.1086/314518

  4. 4.

    Black R. E., Craun G. F., Blake P. A. Epidemiology of common-source outbreaks of shigellosis in the United States, 1961-1975. Am J Epidemiol. 1978;108(1):47-52.

    Not in our library

  5. 5.

    Bokete T. N., O'Callahan C. M., Clausen C. R., Tang N. M., Tran N., Moseley S. L., Fritsche T. R., Tarr P. I. Shiga-like toxin-producing Escherichia coli in Seattle children: a prospective study. Gastroenterology. 1993;105(6):1724-1731.

    Not in our library10.1016/0016-5085(93)91069-t

  6. 6.

    Chalker R. B., Blaser M. J. A review of human salmonellosis: III. Magnitude of Salmonella infection in the United States. Rev Infect Dis. 1988;10(1):111-124.

    Not in our library10.1093/clinids/10.1.111

  7. 7.

    Chomel B. B., DeBess E. E., Mangiamele D. M., Reilly K. F., Farver T. B., Sun R. K., Barrett L. R. Changing trends in the epidemiology of human brucellosis in California from 1973 to 1992: a shift toward foodborne transmission. J Infect Dis. 1994;170(5):1216-1223.

    Not in our library10.1093/infdis/170.5.1216

  8. 8.

    Cohen M. L., Tauxe R. V. Drug-resistant Salmonella in the United States: an epidemiologic perspective. Science. 1986;234(4779):964-969.

    Not in our library10.1126/science.3535069

  9. 9.

    Dennis D. T., Smith R. P., Welch J. J., Chute C. G., Anderson B., Herndon J. L., von Reyn C. F. Endemic giardiasis in New Hampshire: a case-control study of environmental risks. J Infect Dis. 1993;167(6):1391-1395.

    Not in our library10.1093/infdis/167.6.1391

  10. 10.

    Donelli G., Ruggeri F. M., Tinari A., Marziano M. L., Menichella D., Caione D., Concato C., Rocchi G., Vella S. A three-year diagnostic and epidemiological study on viral infantile diarrhoea in Rome. Epidemiol Infect. 1988;100(2):311-320.

    Not in our library10.1017/s0950268800067443

  11. 11.

    Garthright W. E., Archer D. L., Kvenberg J. E. Estimates of incidence and costs of intestinal infectious diseases in the United States. Public Health Rep. 1988;103(2):107-115.

    Not in our library

  12. 12.

    Glass R. I., Noel J., Mitchell D., Herrmann J. E., Blacklow N. R., Pickering L. K., Dennehy P., Ruiz-Palacios G., de Guerrero M. L., Monroe S. S. The changing epidemiology of astrovirus-associated gastroenteritis: a review. Arch Virol Suppl. 1996;12:287-300.

    Not in our library10.1007/978-3-7091-6553-9_31

  13. 13.

    Guerina N. G., Hsu H. W., Meissner H. C., Maguire J. H., Lynfield R., Stechenberg B., Abroms I., Pasternack M. S., Hoff R., Eaton R. B. Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. The New England Regional Toxoplasma Working Group. N Engl J Med. 1994;330(26):1858-1863.

    Not in our library10.1056/nejm199406303302604

  14. 14.

    Hedberg C. W., Savarino S. J., Besser J. M., Paulus C. J., Thelen V. M., Myers L. J., Cameron D. N., Barrett T. J., Kaper J. B., Osterholm M. T. An outbreak of foodborne illness caused by Escherichia coli O39:NM, an agent not fitting into the existing scheme for classifying diarrheogenic E. coli. J Infect Dis. 1997;176(6):1625-1628.

    Not in our library10.1086/517342

  15. 15.

    Herwaldt B. L., Ackers M. L. An outbreak in 1996 of cyclosporiasis associated with imported raspberries. The Cyclospora Working Group. N Engl J Med. 1997;336(22):1548-1556.

    Not in our library10.1056/nejm199705293362202

  16. 16.

    Hlady W. G., Klontz K. C. The epidemiology of Vibrio infections in Florida, 1981-1993. J Infect Dis. 1996;173(5):1176-1183.

    Not in our library10.1093/infdis/173.5.1176

  17. 17.

    Hoffman T. A., Ruiz C. J., Counts G. W., Sachs J. M., Nitzkin J. L. Waterborne typhoid fever in Dade County, Florida. Clinical and therapeutic evaluation of 105 bacteremic patients. Am J Med. 1975;59(4):481-487.

    Not in our library10.1016/0002-9343(75)90255-7

  18. 18.

    Holmberg S. D., Blake P. A. Staphylococcal food poisoning in the United States. New facts and old misconceptions. JAMA. 1984;251(4):487-489.

    Not in our library

  19. 19.

    Jin S., Kilgore P. E., Holman R. C., Clarke M. J., Gangarosa E. J., Glass R. I. Trends in hospitalizations for diarrhea in United States children from 1979 through 1992: estimates of the morbidity associated with rotavirus. Pediatr Infect Dis J. 1996;15(5):397-404.

    Not in our library10.1097/00006454-199605000-00004

  20. 20.

    Kilgore P. E., Holman R. C., Clarke M. J., Glass R. I. Trends of diarrheal disease--associated mortality in US children, 1968 through 1991. JAMA. 1995;274(14):1143-1148.

    Not in our library

  21. 21.

    Klotz S. A., Jorgensen J. H., Buckwold F. J., Craven P. C. Typhoid fever. An epidemic with remarkably few clinical signs and symptoms. Arch Intern Med. 1984;144(3):533-537.

    Not in our library10.1001/archinte.144.3.533

  22. 22.

    Levine W. C., Bennett R. W., Choi Y., Henning K. J., Rager J. R., Hendricks K. A., Hopkins D. P., Gunn R. A., Griffin P. M. Staphylococcal food poisoning caused by imported canned mushrooms. J Infect Dis. 1996;173(5):1263-1267.

    Not in our library10.1093/infdis/173.5.1263

  23. 23.

    Levine W. C., Griffin P. M. Vibrio infections on the Gulf Coast: results of first year of regional surveillance. Gulf Coast Vibrio Working Group. J Infect Dis. 1993;167(2):479-483.

    Not in our library10.1093/infdis/167.2.479

  24. 24.

    Levine W. C., Smart J. F., Archer D. L., Bean N. H., Tauxe R. V. Foodborne disease outbreaks in nursing homes, 1975 through 1987. JAMA. 1991;266(15):2105-2109.

    Not in our library

  25. 25.

    Mahon B. E., Mintz E. D., Greene K. D., Wells J. G., Tauxe R. V. Reported cholera in the United States, 1992-1994: a reflection of global changes in cholera epidemiology. JAMA. 1996;276(4):307-312.

    Not in our library

  26. 26.

    Mermin J. H., Townes J. M., Gerber M., Dolan N., Mintz E. D., Tauxe R. V. Typhoid fever in the United States, 1985-1994: changing risks of international travel and increasing antimicrobial resistance. Arch Intern Med. 1998;158(6):633-638.

    Not in our library10.1001/archinte.158.6.633

  27. 27.

    Mishu B., Blaser M. J. Role of infection due to Campylobacter jejuni in the initiation of Guillain-Barré syndrome. Clin Infect Dis. 1993;17(1):104-108.

    Not in our library10.1093/clinids/17.1.104

  28. 28.

    Monto A. S., Koopman J. S. The Tecumseh Study. XI. Occurrence of acute enteric illness in the community. Am J Epidemiol. 1980;112(3):323-333.

    Not in our library10.1093/oxfordjournals.aje.a112998

  29. 29.

    Osterholm M. T., Forfang J. C., Ristinen T. L., Dean A. G., Washburn J. W., Godes J. R., Rude R. A., McCullough J. G. An outbreak of foodborne giardiasis. N Engl J Med. 1981;304(1):24-28.

    Not in our library10.1056/nejm198101013040106

  30. 30.

    Ostroff S. Yersinia as an emerging infection: epidemiologic aspects of Yersiniosis. Contrib Microbiol Immunol. 1995;13:5-10.

    Not in our library

  31. 31.

    Pang X. L., Joensuu J., Vesikari T. Human calicivirus-associated sporadic gastroenteritis in Finnish children less than two years of age followed prospectively during a rotavirus vaccine trial. Pediatr Infect Dis J. 1999;18(5):420-426.

    Not in our library10.1097/00006454-199905000-00005

  32. 32.

    Parashar U. D., Holman R. C., Clarke M. J., Bresee J. S., Glass R. I. Hospitalizations associated with rotavirus diarrhea in the United States, 1993 through 1995: surveillance based on the new ICD-9-CM rotavirus-specific diagnostic code. J Infect Dis. 1998;177(1):13-17.

    Not in our library10.1086/513808

  33. 33.

    Petersen C. Cryptosporidiosis in patients infected with the human immunodeficiency virus. Clin Infect Dis. 1992;15(6):903-909.

    Not in our library10.1093/clind/15.6.903

  34. 34.

    Petersen C. Cryptosporidium and the food supply. Lancet. 1995;345(8958):1128-1129.

    Not in our library10.1016/s0140-6736(95)90972-9

  35. 35.

    Petersen L. R., Cartter M. L., Hadler J. L. A food-borne outbreak of Giardia lamblia. J Infect Dis. 1988;157(4):846-848.

    Not in our library10.1093/infdis/157.4.846

  36. 36.

    Riepenhoff-Talty M., Saif L. J., Barrett H. J., Suzuki H., Ogra P. L. Potential spectrum of etiological agents of viral enteritis in hospitalized infants. J Clin Microbiol. 1983;17(2):352-356.

    Not in our library10.1128/jcm.17.2.352-356.1983

  37. 37.

    Roberts C. L., Morin C., Addiss D. G., Wahlquist S. P., Mshar P. A., Hadler J. L. Factors influencing Cryptosporidium testing in Connecticut. J Clin Microbiol. 1996;34(9):2292-2293.

    Not in our library10.1128/jcm.34.9.2292-2293.1996

  38. 38.

    Rowe P. C., Orrbine E., Lior H., Wells G. A., McLaine P. N. A prospective study of exposure to verotoxin-producing Escherichia coli among Canadian children with haemolytic uraemic syndrome. The CPKDRC co-investigators. Epidemiol Infect. 1993;110(1):1-7.

    Not in our library10.1017/s0950268800050615

  39. 39.

    Schuchat A., Lizano C., Broome C. V., Swaminathan B., Kim C., Winn K. Outbreak of neonatal listeriosis associated with mineral oil. Pediatr Infect Dis J. 1991;10(3):183-189.

    Not in our library10.1097/00006454-199103000-00003

  40. 40.

    Shapiro R. L., Altekruse S., Hutwagner L., Bishop R., Hammond R., Wilson S., Ray B., Thompson S., Tauxe R. V., Griffin P. M. The role of Gulf Coast oysters harvested in warmer months in Vibrio vulnificus infections in the United States, 1988-1996. Vibrio Working Group. J Infect Dis. 1998;178(3):752-759.

    Not in our library10.1086/515367

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