Interleukin 1 beta – a marker of appreciation for the fixed prosthetic restorations evolution

Background. The purpose of modern dental medicine is to restore the patient’s dental system in order to strengthen health, from a functional, comforting and aesthetic point of view. Methods. The study group consisted of 30 patients to whom we inserted dental implants, which were then rehabilitated by overloading, as follows: 18 patients with fixed metal-ceramic prosthetic (12 women, 6 men) and 12 patients with zirconium-ceramic (5 women, 7 men). Interleukin 1 beta (IL1-) was quantified in all patients after implant insertion at 7, 30 and 90 days, and after overloading at 0, 30 and 90 days. Results. The IL1- values correlate with the depth of the peri-implant pocket at all three moments of implant insertion (r>0.600), with a high statistical significance between the 30- and 90-day determinations (p<0.001). After overloading, it was demonstrated that there is a correlation between IL1- values and the depth of the peri-implant pocket at all times of evaluation (metal-ceramic: r between 0.774-0.871, zirconium ceramic: r between 0.679-0.895). Conclusion. The existence of high correlations between peri-implant pocket depth and IL1- supports the utility of IL1- quantification as a parameter for monitoring patients after insertion of dental implants. For both types of dental materials, the value of IL1- is the expression of gingival tissue remodeling after fixed denture prosthesis. Values of IL1- quantified in the peri-implant fluid show the superiority of the zirconium-ceramic material compared to the metal-ceramic material.

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