Endometrial polyps in postmenopausal women: results of a comparative analysis of clinical features after hysteroscopic polypectomy

Aim. To evaluate the clinical features of endometrial polyps (EP) in postmenopausal patients based on a comparative analysis of symptomatic and asymptomatic forms. Мaterials and methods. A retrospective cohort study was conducted with the inclusion of 92 postmenopausal women who underwent hysteroscopic polypectomy in the gynecological Department of the Clinical Hospital of Russian Railways-Medicine Omsk in 20182019. Тhe аverage age of patients was 60.356.56 years. Two groups of patients were identified: group 1 included patients with asymptomatic EP (n=64), group 2 women with EP associated with uterine bleeding (n=28). Results. Postmenopausal EP patients had: asymptomatic (69.6%), uterine bleeding (30.4%), recurrent EP (14.3%), concomitant tamoxifen treatment (5.4%), single (77.2%) and multiple (22.8%) EP. In group 1, patients with late postmenopausal stage (73.4%) with single EP (76.6%) of various localization, glandular-fibrotic type (78.1%, p0.05) prevailed. Group 2 was dominated by patients with early postmenopausal stage (60.7%, p0.05) with single EP (78.6%, p0.05) of various localization, having glandular (50%, p0.01), glandular-fibrotic (46.4%, p0.01) EP and adenomatous EP with malignancy (3.57%, p0.05). Hyperplasia of endometrium was observed in both groups (1.56 and 3.57% in group 1 and 2, respectively), and adenocarcinoma in group 1 (1.56%). Conclusion. In patients with postmenopausal EP, along with a benign course, the disease occurs against the background of atypical hyperplasia and endometrial cancer (in the polyp or endometrium) in 3,3% of cases, including the asymptomatic nature of the disease.

Abstract licence: CC BY

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