From the DNA Gyrase Inhibitor Cyclothialidine to a New Class of Antibacterial Agents
Erwin Goetschi, Fabienne Ricklin, Peter Reindl and 8 more
CHIMIA · 2003
doi:10.2533/000942903777679505 (opens in a new tab)
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Abstract
Cyclothialidine (Ro 09-1437) is a potent DNA gyrase inhibitor that was isolated from S. filipinensis NR0484. In this account we describe the identification of potent antibacterials structurally derived from this virtually neat enzyme inhibitor.
Abstract licence: CC BY-NC
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