Analytical investigation of transient molecular-motor-assisted transport in elongated cells

This paper investigates analytically the molecular-motor-assisted transport between the cell nucleus and cell membrane in an elongated cell, which allows the formulation of governing equations in a cylindrical coordinate system. This problem is relevant to biomimetic transport systems as well as to many biological processes occurring in living cells, such as the viral infection of a cell. The obtained analytical solution is shown to agree well with a high-accuracy numerical solution of the same problem. The developed analytical technique extends the applicability of the generalized Fourier series method to a new type of problems involving intracellular transport of organelles.

Abstract licence: CC BY-NC-ND

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