PEG mediated synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones using Castro-Stephen coupling, oxidation and cyclocondensation reactions
Pagilla Shankaraiah, Kumar Angajala Kishore, Sunitha Vianala and 1 more
Journal of the Serbian Chemical Society · 2020
doi:10.2298/jsc190517014p (opens in a new tab)
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Abstract
A PEG-mediated green synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin- 4(3H)-ones was developed starting from 6-iodo-3-methyl-2-phenylquinazolin- 4(3H)-one by means of quinazolinone-based internal alkyne/1,2-diketone as intermediates using the Castro–Stephen coupling reaction/potassium permanganate mediated oxidation and cyclocondensation reactions.
Abstract licence: CC BY
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