An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves
Krstić Ljubomir, Sukdolak Slobodan, Solujić-Sukdolak Slavica
Journal of the Serbian Chemical Society · 2002
doi:10.2298/jsc0205325k (opens in a new tab)
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Abstract
The microwave promoted reaction of warfarin with methanol, or ethanol, in the presence of montmorillonite clay K-10 as a catalyst, affords the corresponding acetals, 2-methoxy 2-methyl-4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one (2) and 2-ethoxy-2-methyl- 4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one (3) respectively, in good yields.
Abstract licence: CC BY
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