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The isolation of (6S, 9S)-cyclo (prolylvalyl) from marine actinomycete, by use of high speed contercurrent chromatography

Šmelcerović Andrija A., Schiebel Mirko, Đorđević Siniša M.

Journal of the Serbian Chemical Society · 2002

doi:10.2298/jsc0201027s (opens in a new tab)

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Abstract

The marine actinomycete B 1758 came from the actinomycete collection of the Alfred Wegener Institute for Polar and Marine Research in Bremerhafen Germany. 1.079 g of raw extract was obtained by fermentation. Seven fractions were separated by column chromatography on silica gel. Fraction 4 was separated by high speed countercurrent chromatography. Fraction 4.6 yielded 5.2 mg of (6S, 9S)-cyclo(prolylvalyl).

Abstract licence: CC BY

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