An alternative synthesis of clindamycin
Bowden Keith, Stevens Graham P.
Journal of the Serbian Chemical Society · 2000
doi:10.2298/jsc0010691b (opens in a new tab)
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Abstract
A novel synthesis of clindamycin from lincomycin using N-chlorosuccinimide and triphenylphosphine is reported. This results in high yields and avoids the use of tetrachloromethane employed in the current manufacturing process. <br><br><font color="red"><b> This article has been corrected. Link to the correction <u><a href="http://dx.doi.org/10.2298/JSC0012975E">10.2298/JSC0012975E</a><u></b></font>
Abstract licence: CC BY
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