Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
Maryam Barekat, Mohammad Amin Shahrbaf, Kosar Rahi and 1 more
Cell Journal · 2022
doi:10.22074/cellj.2022.8487 (opens in a new tab)
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Abstract
There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of themare in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cellsthrough the renin-angiotensin system (RAS) via the angiotensin-converting enzyme 2 (ACE2) receptor. RAS activationis associated with pro-inflammatory effects through the ACE/Ang II/ Angiotensin II type 1 receptor (AT1R) pathwayor anti-inflammatory effects through ACE2/Ang1-7/Mas axis. In the current paper, we discuss the pathophysiology ofnewly diagnosed HTN and its effect on morbidity in patients with coronavirus disease 2019 (COVID-19).
Abstract licence: CC BY-NC
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