Effects of ginger capsule on treatment of nausea and vomiting in patients receiving cisplatin undergoing mastectomy: a randomized clinical trial

Introduction: Nausea and vomiting is one of the most common and undesirable side effects of cisplatin and due to the effects of ginger in the treatment and prevention of nausea and vomiting, this study was performed with aim to evaluate the effect of ginger capsule on treatment of nausea and vomiting in patients receiving cisplatin undergoing mastectomy. Methods:This randomized clinical trial study was performed on 60 cancer patients in the chemotherapy clinic of Tabriz Shahid Madani Hospital in 2018-2019. The intervention group received ginger tablet 500 mg twice daily from 10th days after chemotherapy and one week before mastectomy. The control group received placebo tablet. Rhodes nausea and vomiting assessment tool was used before the intervention and the day after mastectomy. Data were analyzed by SPSS software (version 21) and Shapiro-Wilk and t-test. P<0.05 was considered statistically significant. Results: The intra-group comparison showed the control group had no significant difference in terms of nausea severity after the intervention (p=0.119), whereas a significant difference was observed in the intervention group after the intervention (p=0.001). There was no significant change in vomiting severity in the control group (p=0.229), while this score was significantly decreased in the intervention group (p=0.004). Conclusion: Ginger capsule is effective in treatment nausea and vomiting in women who have used cisplatin and are going to undergo mastectomy.

Abstract licence: CC BY-ND

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