A New View of a:C-H-coated Ti-6Al-4V Alloy to be Used as Orthopedic Implants: Influence of Surface Free-energy of Interaction on the Biological Responses

<p>In a previous published work, the Ti-6Al-4V alloy were functionalized by using plasma enhanced chemical vapour deposition (PECVD) process in order to obtain hydrogenated amorphous carbon (a:C-H) on the biomaterial's surface. At the time, we noticed the functionalized surface contributed to the advance of using Ti-6Al-4V in biomedical implants applications as well as in the adding of intrinsic properties as demonstrated by electrochemical and biological assays. Here, we present new view of a-C:H-coated Ti-6Al-4V alloy, considering the influence of surface free-energy of interaction and understanding how the surface influences the biological response using pre-osteoblastic cells (MC3T3-61). Our results demonstrate, the Ti-6Al-4V containing a:C-H film has less negative value of surface free-energy when compared to the bare material (-22.156 mJ m^-2 <em>vs.</em> -60.046 mJ m^-2), suggesting a tendency toward to a less hydrophobic surface which is extremely important to reduce the inflammatory process, common in orthopedic implants.</p><p> </p><p>DOI: <a href="http://dx.doi.org/10.17807/orbital.v13i3.1622">http://dx.doi.org/10.17807/orbital.v13i3.1622</a></p><p> </p>

Abstract licence: CC BY-NC-ND

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