Perfil funcional de pacientes portadores de seqüela de tuberculose de um hospital universitário Functional profile of patients with tuberculosis sequelae in a university hospital

OBJETIVO: Descrever os dados de função pulmonar de pacientes com seqüela de tuberculose pulmonar, pleural e pleuropulmonar. MÉTODOS: Em um ambulatório de tuberculose de um hospital universitário, de 218 pacientes atendidos, 56 tinham seqüela de tuberculose pulmonar, pleural e pleuropulmonar, e 162 tiveram outros tipos de tuberculose. No laboratório de função pulmonar, 43 foram elegíveis para o estudo, de fevereiro de 2000 a julho de 2004. Foram excluídos os pacientes com doenças prévias, como: asma; doença pulmonar obstrutiva crônica; insuficiência cardíaca; doenças do colágeno; silicose; cirurgia torácica prévia; e espirometria inaceitável ou não realizada. Os campos pulmonares foram divididos em seis zonas e os radiogramas classificados em: grau I, com mínimo envolvimento em somente uma zona sem cavitação; grau II, com envolvimento de duas ou três zonas ou uma zona com cavitação; grau III, com envolvimento grave em mais de três zonas com ou sem cavitação. RESULTADOS: Cinqüenta pacientes foram incluídos no estudo e 44 deles tiveram tuberculose pulmonar (88%). O distúrbio ventilatório combinado foi o mais prevalente, 17/50 (34%). Os distúrbios acentuados foram mais significativos no grau III (p = 0,0002). A função pulmonar normal predominou nos graus I e II (p = 0,002). CONCLUSÃO: A descoberta e o tratamento precoce dos casos de tuberculose pulmonar contribuem para a diminuição dos casos da doença e de suas seqüelas, melhorando a qualidade de vida desses pacientes. Os autores sugerem uma análise logitudinal e seqüencial (protocolo), com maior número de pacientes com seqüelas de tuberculose nos serviços de referência no Brasil.<br>OBJECTIVE: To describe data related to the pulmonary function of patients with sequelae of pulmonary tuberculosis, pleural tuberculosis or both. METHODS: In the outpatient clinic of a university hospital, 218 patients were evaluated. Of those 218, 56 had sequelae of tuberculosis (pulmonary, pleural or both), and 162 had other types of tuberculosis. All patients were evaluated in the pulmonary function laboratory between February 2000 and July 2004, and 43 were found to be eligible for inclusion in the study. Patients with a history of asthma, chronic pulmonary obstructive disease, cardiac insufficiency, collagen diseases, silicosis or thoracic surgery, as well as those for whom spirometry yielded unacceptable results or was not performed, were excluded. The lung fields were divided into six zones, and radiographic results were classified by degree: I (involvement of only one zone with no cavitation); II (involvement of two or three zones or of one zone with cavitation); or III (extensive involvement of three or more zones with or without cavitation). RESULTS: The final study sample comprised 50 patients, 44 (88%) of whom had pulmonary tuberculosis. The most prevalent form (17/50; 34%) was mixed ventilatory disturbance. Severe disturbances were more significant in degree III radiographs (p = 0.0002) and normal pulmonary function was predominant among patients presenting degree I and II radiographs (p = 0.002). CONCLUSION: The early discovery and treatment of tuberculosis contribute to reduce the number of cases, as well as the incidence of tuberculosis sequelae, thereby improving the quality of life of tuberculosis patients. Further studies, involving longitudinal, sequential analysis and larger samples of patients with tuberculosis sequelae, should be conducted in referral centers in Brazil.

Abstract licence: CC BY-NC

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