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Editorial Comment: Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control

Marcio Augusto Averbeck

International Brazilian Journal of Urology · 2020

doi:10.1590/s1677-5538.ibju.2020.02.10 (opens in a new tab)

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Abstract

There is increasing evidence for a possible causal association between the chronic use of anticholinergics and the risk of developing dementia. The inherent limitation for establishing such causal nexus is precisely the fact that the prevalence of overactive bladder (OAB) symptoms and the prescription of antimuscarinics tends to increase in older individuals, exactly in the same age groups in which the incidence of dementia is higher (1).

Abstract licence: CC BY

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