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Skeletal muscle ischemia and reperfusion in rats increase lipid peroxidation in rats Isquemia e reperfusão do músculo esquelético aumenta a peroxidação lipídica em ratos

Carlos Eli Piccinato, Armando De Domenico Jr, Alceu Afonso Jordão Jr and 1 more

Acta Cirúrgica Brasileira · 2004

doi:10.1590/s0102-86502004000500018 (opens in a new tab)

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Abstract

PURPOSE: To determine the effects of 30 minutes of ischemia followed by 30 minutes of reperfusion in skeletal muscle of rats receiving three different diets (supplemented, normal and vitamin E deficient) on lipoperoxidation (LP). METHODS: LP measured by TBARS levels, and plasma and hepatic concentrations of vitamin E measured by HPLC. RESULTS: The deficient group presented higher lipoperoxidation levels in muscle compared to the control and supplemented groups. CONCLUSION: Supplementation with vitamin E decrease the free radicals production in ischemia/reperfusion in skeletal muscle of rats.

Abstract licence: CC BY

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