Evaluation of Antiproliferative Potential of Cerium Oxide Nanoparticles on HeLa Human Cervical Tumor Cell
Zoriţa Diaconeasa, Lucian Barbu Tudoran, Cristina Coman and 5 more
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology · 2015
doi:10.15835/buasvmcn-fst:11138 (opens in a new tab)
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Abstract
Cerium oxide nanoparticles (CeO2 nanoparticles) as nanomaterials have promising biomedical applications. In this paper, the cytotoxicity induced by CONPs human cervical tumor cells was investigated. Cerium oxide nanoparticles were synthesized using the precipitation method. The nanoparticles were found to inhibit the proliferation of HeLa human cervical tumor cells in a dose dependent manner but did not showed to be cytotoxic as analyzed by MTT assay. The administrated treatment decreased the HeLa cell viability cells from 100% to 65% at the dose of 100 μg/mL.
Abstract licence: CC BY-NC-ND
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