Correlation between Energy Expenditure and Nitrogen Losses in Patients with Acute Cerebral Damage of Vascular and Traumatic Genesis

Objective: to study whether there is an association between urea nitrogen (UN) excretion and carbon dioxide (VCO2) elimination and its magnitude in patients with acute cerebral damage of vascular and traumatic genesis. Subjects and methods. The 2007—2009 prospective study enrolled 16 adult patients of both sexes on prolonged mechanical ventilation who were diagnosed as having brain injury and hemorrhagic stroke. Fifty-two pair measurements of VCO2 and UN were made. Correlation analysis revealed a significant statistical dependence of the parameters: r=0.653; t=6.102; pConclusion. The clinical markers of increased metabolic processes and enhanced protein catabolism are in a statistically significant correlation. A formula has been derived for a current energy expenditure-UN value relationship. The results of estimation of energy expenditure from the value of UN, by taking into account the regression analysis coefficient and by applying the indirect calometry technique, do not differ. Key words: energy expenditure, Harris-Benedict method, urea nitrogen excretion.

Abstract licence: CC BY

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