Melkersson-Rosenthal Syndrome: A forgotten diagnosis

The rare, non-caseating, granulomatous disease known as Melkersson-Rosenthal syndrome (MRS) can be diagnostically difficult especially when not presenting as the characteristic triad of facial palsy, facial edema, and fissured tongue.1 We present a case of a 65-year-old female with a 15-year history of recurrent bilateral upper eyelid swelling previously unsuccessfully treated for a presumed lid allergy and rosacea. Following imaging and histopathology results, she has now been diagnosed with Melkersson-Rosenthal syndrome. Since this disease is typically refractory to treatment, she is being followed and treated with cosmetic eyelid skin reduction if necessary during inactive stages of the disease.

Abstract licence: CC BY

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