Elevated Post-transplant Levels of Neopterin are Associated with Poorer long-term Graft Outcome
Grebe S. O., Kuhlmann U., Müller T. F.
Pteridines · 2004
doi:10.1515/pteridines.2004.15.3.113 (opens in a new tab)
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Abstract
Chronic allograft nephropathy (CAN) and death with functioning graft due to cardiovascular disease (CVD) are the key determinants for long-term renal allograft survival. Chronic allograft nephropathy and cardiovascular disease are seen as manifestations of a single disease entity with a common pathogenesis including inflammation and accelerated atherogenesis. Therefore we investigated the relation between early post-transplant inflammatory burden and long-term graft survival.
Abstract licence: CC BY
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