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ABSTRACTS 11th International Symposium on Chemistry and Biology of Pteridines and Folates

Pfleiderer Wolfgang, Rokos Konstanz, Rokos Hartmut

Pteridines · 1997

doi:10.1515/pteridines.1997.8.2.103 (opens in a new tab)

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Abstract

Neopterin, 6-( D-erythro-1 ,2,3-trihydroxypropyl)pterin, is the biochemical indicator for activity of cellular immune response, which is produced by responded macrophages by interferon-gamma. If there are diseases related with T-cell such as, tuberculosis' viral disease, AIDS, and cellular allograft rejection, lots of neopterin are produced in body and then extruded out. The chemical syn-Pteridines/ Vol. 8 / No. 2 11'" International Symposium on Chemistry and Biology of Pteridines and Folates/ Poster Presentations thesis of neopterin is produced by the oxidation of 5,6-dihydro-6-( 1 ,2,3-trihydroxypropyl)pteridine with O 2 which was yielded condensation of 5,6-diaminopyrimidine and phenylhydrazones of D-and L-arabinose under acidic condition.

Abstract licence: CC BY

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