Recent advances in the analysis of nanotube-reinforced polymeric biomaterials

Conventional experimental or computational techniques are often inadequate for the analysis and development of nanocomposite-based materials as they are tedious (e.g., experimental methods) or are unsuitable to capture the properties of these novel materials (e.g., conventional computational techniques), thereby requiring multiscale computational strategies. During the last 5 years, major developments were made by the authors on the formulation and implementation of multiscale computational models, using atomistic simulation and micro-mechanics-based techniques, to study the mechanical and thermal behavior of nanocomposite-based materials. In this article, the advances made in the computational analysis of nanocomposites for tissue engineering applications (e.g., scaffolds and bioreactors) would be discussed. The material properties of the nanocomposites in the lower scales were determined using molecular dynamics, and were then transferred to the macroscale using various homogenization techniques. Also in this article, the authors discuss the development of a theory of mixture-based finite element model for nutrient flow in a hollow fiber membrane bioreactor and the use of computational tools to improve the efficiency of the bioreactor.

Abstract licence: CC BY

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.