Use of Circulating and Cellular miRNAs Expression in Forensic Sciences

The current practice in the field of forensic medicine imposes the use of modern investigation techniques. The complexity of laboratory investigation methods needed for a final result of the investigation in forensic medicine needed new biomarkers of higher specificity and selectivity. Such biomarkers are the microRNAs (miRNAs), short, non-coding RNAs composed of 19–24 nucleotides. Their characteristics, such as high stability, selectivity, and specificity for biological fluids, differ from tissue to tissue and for certain pathologies, turning them into the ideal candidate for laboratory techniques used in forensic medicine. In this paper, we wish to highlight the biochemical properties and the usefulness of miRNAs in forensic medicine.

Abstract licence: CC BY-NC-ND

1. 21.

   Genome-wide survey of tissue-specific microRNA and transcription factor regulatory networks in 12 tissues · 2014

2. 31.

   MicroRNA Fingerprints Identify miR-150 as a Plasma Prognostic Marker in Patients with Sepsis · 2009

3. 38.

   Exposure to Metal-Rich Particulate Matter Modifies the Expression of Candidate MicroRNAs in Peripheral Blood Leukocytes · 2010

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