Aurora kinases orchestrate mitosis; who are the players?
Molla Annie
Biomolecular Concepts · 2010
doi:10.1515/bmc.2010.014 (opens in a new tab)
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Abstract
The Aurora are a conserved family of serine/threonine kinases with essential functions in cell division. In mitosis, Aurora kinases are required for chromosome segregation, condensation and orientation in the metaphase plate, spindle assembly, and the completion of cytokinesis. This review presents the Aurora kinases, their partners and how their interactions impact on the different mitotic functions.
Abstract licence: CC BY
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