Binding and entering: COVID finds a new home.
Michelle N Vu, Vineet D Menachery
PLoS Pathogens · 2021
doi:10.1371/journal.ppat.1009857 (opens in a new tab)
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Abstract
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged as a virus with a pathogenicity closer to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and a transmissibility similar to common cold coronaviruses (CoVs). In this review, we briefly discuss the features of the receptor-binding domain (RBD) and protease cleavage of the SARS-CoV-2 spike protein that enable SARS-CoV-2 to be a pandemic virus.
Abstract licence: CC BY
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