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Expression of Concern: Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor.

PLOS ONE Editors

PLoS ONE · 2019

doi:10.1371/journal.pone.0223138 (opens in a new tab)

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Abstract

After publication of this article [1], several concerns were raised for Figs 3, 4 and 6: • In Fig 3A, there appears to be overlap between the following image pairs, suggesting that all four of the affected panels may represent data from the same slide:• DR4 TRAIL panel (row 1, column 3) and DR5 Resveratrol panel (row 2, column 2)• DR5 Resveratrol panel and DR5 TRAIL panel (row 2, column 3)• DR4 Resveratrol panel (row 1, column 2) and DR5 TRAIL panelThe authors provide here an updated version of Fig 3A in which they replaced all panels for the DR4 and DR5 immunohistochemistry experiments.

Abstract licence: CC BY

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