Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1α protein synthesis.

Cited by papers we hold 4

• Targeting Drug Chemo-Resistance in Cancer Using Natural Products · 2021
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• Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements · 2019
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• Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science · 2019
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• Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases · 2017
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