Foldscope: Origami-Based Paper Microscope

Abstract

Here we describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes, specifically demonstrating brightfield, darkfield, and fluorescence microscopes. Merging principles of optical design with origami enables high-volume fabrication of microscopes from 2D media. Flexure mechanisms created via folding enable a flat compact design. Structural loops in folded paper provide kinematic constraints as a means for passive self-alignment. This light, rugged instrument can survive harsh field conditions while providing a diversity of imaging capabilities, thus serving wide-ranging applications for cost-effective, portable microscopes in science and education.

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• An Assemblable, Multi-Angle Fluorescence and Ellipsometric Microscope. · 2016
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• Open Labware: 3-D Printing Your Own Lab Equipment · 2015
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