Past and future epidemic potential of chikungunya virus in Australia.

<h4>Background</h4>Australia is theoretically at risk of epidemic chikungunya virus (CHIKV) activity as the principal vectors are present on the mainland Aedes aegypti) and some islands of the Torres Strait (Ae. aegypti and Ae. albopictus). Both vectors are highly invasive and adapted to urban environments with a capacity to expand their distributions into south-east Queensland and other states in Australia. We sought to estimate the epidemic potential of CHIKV, which is not currently endemic in Australia, by considering exclusively transmission by the established vector in Australia, Ae. aegypti, due to the historical relevance and anthropophilic nature of the vector.<h4>Methodology/principal findings</h4>We estimated the historical (1995-2019) epidemic potential of CHIKV in eleven Australian locations, including the Torres Strait, using a basic reproduction number equation. We found that the main urban centres of Northern Australia could sustain an epidemic of CHIKV. We then estimated future trends in epidemic potential for the main centres for the years 2020 to 2029. We also conducted uncertainty and sensitivity analyses on the variables comprising the basic reproduction number and found high sensitivity to mosquito population size, human population size, impact of vector control and human infectious period.<h4>Conclusions/significance</h4>By estimating the epidemic potential for CHIKV transmission on mainland Australia and the Torres Strait, we identified key areas of focus for controlling vector populations and reducing human exposure. As the epidemic potential of the virus is estimated to rise towards 2029, a greater focus on control and prevention measures should be implemented in at-risk locations.

Abstract licence: CC BY

1. 5.

   Australia's Dengue Risk Driven by Human Adaptation to Climate Change · 2009

2. 8.

   Vectorial Capacity of Aedes aegypti: Effects of Temperature and Implications for Global Dengue Epidemic Potential · 2014

3. 11.

   A Single Mutation in Chikungunya Virus Affects Vector Specificity and Epidemic Potential · 2007

4. 12.

   Impact of Wolbachia on Infection with Chikungunya and Yellow Fever Viruses in the Mosquito Vector Aedes aegypti · 2012

5. 36.

   Scaled deployment of Wolbachia to protect the community from dengue and other Aedes transmitted arboviruses · 2019

6. 40.

   Global expansion and redistribution of Aedes-borne virus transmission risk with climate change · 2019

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