Tropical diseases research: thirty years and counting.

was launched in 1978, more or less the same year I began my career in science as a Yale undergraduate working on the then nascent molecular biology of antigenic variation in African trypanosomes. Over the next two decades as a MD PhD student working on hookworms at Rockefeller University, and then back at Yale as a postdoctoral fellow and a member of the junior faculty there, I was told on multiple occasions that the likelihood of my making a career in scientific research on neglected tropical diseases was not very promising. After all, neglected diseases were neglected for a reason, including the fact that the most promising options for my obtaining long-term support at that time were (by today’s standards) relatively modest funds from the Rockefeller Foundation, the John

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