A global biomedical R&D fund and mechanism for innovations of public health importance.

Over the last few years, there have been significant challenges in and increased concerns around anti-microbial resistance (AMR), emerging infectious diseases, and neglected diseases (NDs).Both AMR and emerging infectious diseases, specifically Ebola, have recently been elevated to the level of public health concerns affecting global security.All these areas have identifiable prevention and management strategies that can and should be scaled up.However, an additional consistent thread that runs throughout all these global health concerns is the deficit in innovation of new tools in relation to the identified needs.Therapeutics and vaccines for Summary Points• Anti-microbial resistance, emerging infectious diseases, and neglected diseases are all important public health concerns and priorities with serious market failures, deficits, and identified needs in biomedical innovation.• It is important to reconcile, rather than fragment, the needs of these three priority areas by considering an umbrella framework for specifically financing and coordinating research and development (R&D) that delivers innovation while securing patient access.• A sizeable, sustainably financed global R&D fund and mechanism that promotes coordination, collaboration, and utilization of new and innovative incentives should be set up to cover all three priority areas.

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