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Assessing Vaccination Sentiments with Online Social Media: Implications for Infectious Disease Dynamics and Control

Marcel Salathé, Shashank Khandelwal

PLoS Computational Biology · 2011

doi:10.1371/journal.pcbi.1002199

Abstract

There is great interest in the dynamics of health behaviors in social networks and how they affect collective public health outcomes, but measuring population health behaviors over time and space requires substantial resources. Here, we use publicly available data from 101,853 users of online social media collected over a time period of almost six months to measure the spatio-temporal sentiment towards a new vaccine. We validated our approach by identifying a strong correlation between sentiments expressed online and CDC-estimated vaccination rates by region. Analysis of the network of opinionated users showed that information flows more often between users who share the same sentiments - and less often between users who do not share the same sentiments - than expected by chance alone. We also found that most communities are dominated by either positive or negative sentiments towards the novel vaccine. Simulations of infectious disease transmission show that if clusters of negative vaccine sentiments lead to clusters of unprotected individuals, the likelihood of disease outbreaks is greatly increased. Online social media provide unprecedented access to data allowing for inexpensive and efficient tools to identify target areas for intervention efforts and to evaluate their effectiveness.

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References 26

  1. 1.

    Jansen VAA, Stollenwerk N, Jensen HJ, Ramsay ME, Edmunds WJ, et al. Measles outbreaks in a population with declining vaccine uptake. Science. 2003;301:804.

    Not in our library10.1126/science.1086726

  2. 2.

    Salathé M, Bonhoeffer S. The effect of opinion clustering on disease outbreaks. J R Soc Interface. 2008;5:1505-1508.

    Not in our library10.1098/rsif.2008.0271

  3. 3.

    Omer SB, Salmon DA, Orenstein WA, deHart MP, Halsey N. Vaccine refusal, mandatory immunization, and the risks of vaccine-preventable diseases. N Engl J Med. 2009;360:1981-1988.

    Not in our library10.1056/nejmsa0806477

  4. 4.

    Christakis NA, Fowler JH. The spread of obesity in a large social network over 32 years. N Engl J Med. 2007;357:370-379.

    Not in our library10.1056/nejmsa066082

  5. 5.

    Christakis NA, Fowler JH. The collective dynamics of smoking in a large social network. N Engl J Med. 2008;358:2249-2258.

    Not in our library10.1056/nejmsa0706154

  6. 6.

    Centola D. The spread of behavior in an online social network experiment. Science. 2010;329:1194-1197.

    Not in our library10.1126/science.1185231

  7. 7.

    Mokdad AH, Remington PL. Measuring health behaviors in populations. Prev Chronic Dis. 2010;7:A75.

    Not in our library

  8. 8.

    Eysenbach G, Powell J, Englesakis M, Rizo C, Stern A. Health related virtual communities and electronic support groups: systematic review of the effects of online peer to peer interactions. BMJ. 2004;328:1166.

    Not in our library10.1136/bmj.328.7449.1166

  9. 9.
  10. 10.

    Ginsberg J, Mohebbi MH, Patel RS, Brammer L, Smolinski MS, et al. Detecting influenza epidemics using search engine query data. Nature. 2009;457:1012-1014.

    Not in our library10.1038/nature07634

  11. 11.
  12. 12.

    Interim results: state-specific influenza A (H1N1) 2009 monovalent vaccination coverage - United States, October 2009-January 2010. MMWR Morb Mortal Wkly Rep. 2010;59:363-368.

    Not in our library

  13. 13.

    Newman M. Mixing patterns in networks. Phys Rev E Stat Nonlin Soft Matter Phys. 2003;67:026126.

    Not in our library10.1103/physreve.67.026126

  14. 14.

    Reichardt J, Bornholdt S. Statistical mechanics of community detection. Phys Rev E Stat Nonlin Soft Matter Phys. 2006;74:016110.

    Not in our library10.1103/physreve.74.016110

  15. 15.

    Salathé M, Kazandjieva M, Lee JW, Levis P, Feldman MW, et al. A high-resolution human contact network for infectious disease transmission. Proc Nat Acad Sci U S A. 2010;107:22020-22025.

    Not in our library10.1073/pnas.1009094108

  16. 16.

    Ten great public health achievements--United States, 1900-1999. MMWR Morb Mortal Wkly Rep. 1999;48:241-243.

    Not in our library

  17. 17.

    Ash C. Summun bonum. Sci Transl Med. 2010;2:61ed8.

    Not in our library10.1126/scitranslmed.3001924

  18. 18.

    Anderson RM, May RM, Anderson B. Infectious Diseases of Humans: Dynamics and Control (Oxford Science Publications). 1992.

    Not in our library

  19. 19.

    Feikin DR, Lezotte DC, Hamman RF, Salmon DA, Chen RT, et al. Individual and community risks of measles and pertussis associated with personal exemptions to immunization. JAMA. 2000;284:3145-3150.

    Not in our library10.1001/jama.284.24.3145

  20. 20.

    May T, Silverman RD. “Clustering of exemptions” as a collective action threat to herd immunity. Vaccine. 2003;21:1048-1051.

    Not in our library10.1016/s0264-410x(02)00627-8

  21. 21.

    Sugerman DE, Barskey AE, Delea MG, Ortega-Sanchez IR, Bi D, et al. Measles Outbreak in a Highly Vaccinated Population, San Diego, 2008: Role of the Intentionally Undervaccinated. Pediatrics. 2010;125:747-755.

    Not in our library10.1542/peds.2009-1653

  22. 22.

    Lazer D, Pentland A, Adamic L, Aral S, Barabasi A, et al. Computational social science. Science. 2009;323:721-723.

    Not in our library10.1126/science.1167742

  23. 23.

    Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the United States, 2000. JAMA. 2004;291:1238-1245.

    Not in our library10.1001/jama.291.10.1238

  24. 24.

    Bird S, Klein E, Loper E. Natural Language Processing with Python. 1st ed. O'Reilly Media. 2009;512.

    Not in our library

  25. 25.

    Ferguson N, Cummings D, Cauchemez S. Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature. 2005;437:209-14.

    Not in our library10.1038/nature04017

  26. 26.

    Lessler J, Reich N. Outbreak of 2009 pandemic influenza A (H1N1) at a New York City school. N Engl J Med. 2009;361:2628-2636.

    Not in our library10.1056/nejmoa0906089

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