Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association
Elisabete Pereira Coelho, Ana Rita Matos, Sofia Caridade
European Journal of Case Reports in Internal Medicine · 2019
doi:10.12890/2019_001352 (opens in a new tab)
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Abstract
A woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted. Laboratory investigations revealed hyperbilirubinemia, hypergammaglobulinemia and positive anti-smooth muscle antibodies. Histologic examination of the skin was compatible with scleroderma. Histologic examination of the liver was suggestive of autoimmune and alcoholic hepatitis.
Abstract licence: CC BY-NC-ND
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