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Pulmonary Arteriovenous Malformation can be Associated with Embolic Stroke of Undetermined Source (ESUS)

Mariana Barros Cruz, Nuno Palma, Joao Rocha and 1 more

European Journal of Case Reports in Internal Medicine · 2019

doi:10.12890/2019_001262 (opens in a new tab)

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Abstract

Pulmonary arteriovenous malformations (PAVMs) are rare vascular anomalies. Alternative designations are pulmonary arteriovenous fistulae or aneurysms. Although mostly asymptomatic, PAVMs can cause respiratory symptoms due to right-to-left shunt. The central nervous system is a potential target for complications, including stroke, as a result of paradoxical embolism. In this report, the authors describe an unusual case of cerebral emboli caused by paradoxical embolism through a PAVM, presenting with a broad pathology including orthodeoxia, central cyanosis and digital clubbing, which should be kept in mind since misdiagnosis may cause severe morbidity in young adults.

Abstract licence: CC BY-NC-ND

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