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Bilateral Panuveitis at Etanercept Initiation for Juvenile Idiopathic Arthritis

Kaouther Ben Abdelghani, Marwa Slouma, Rym Hajri and 2 more

European Journal of Case Reports in Internal Medicine · 2014

doi:10.12890/2014_000036 (opens in a new tab)

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Abstract

Introduction: Uveitis is a well-known extra-rheumatological manifestation of juvenile idiopathic arthritis (JIA). Tumour necrosis factor(TNF) has been used to treat uveitis associated with inflammatory diseases. A new-onset uveitis under anti-TNF therapy is uncommon. Case presentation: A 12-year-old male, affected since the age of 6 years, by a severe form of polyarticular JIA. When etanercept was started, hepresented panuveitis bilaterally, so we switched to infliximab with good response. Conclusions: The TNF-soluble receptor could be considered as a possible promoter in inducing endogenous new-onset uveitis in JIA.

Abstract licence: CC BY-NC-ND

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